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| | Z-VEID-AFC Basic information |
| Product Name: | Z-VEID-AFC | | Synonyms: | N-[(Phenylmethoxy)carbonyl]-L-valyl-L-alpha-glutamyl-L-isoleucyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine;MCA-VDQVDGWK(DNP)-NH2;MCA-VQVDGW-K(DNP)-NH2;MCA-VAL-ASP-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;MCA-VAL-GLN-VAL-ASP-GLY-TRP-LYS(DNP)-NH2;CASPASE-6 SUBSTRATE III, FLUOROGENIC;CASPASE 6 (MCH2) SUBSTRATE 2, FLUOROGENIC;CASPASE-6, SUBSTRATE, FLUOROGENIC | | CAS: | 219138-06-4 | | MF: | C38H44F3N5O12 | | MW: | 819.78 | | EINECS: | | | Product Categories: | Pepetides;peptide | | Mol File: | 219138-06-4.mol |  |
| | Z-VEID-AFC Chemical Properties |
| Boiling point | 1087.7±65.0 °C(Predicted) | | density | 1.380±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO/DMF: 20 mM | | pka | 4.09±0.10(Predicted) | | form | powder | | Sequence | {Z}-Val-Glu-Ile-Asp-{AFC} |
| | Z-VEID-AFC Usage And Synthesis |
| Uses | Z-VEID-AFC is a fluorescent substrate for caspase-6[1]. | | Biological Activity | Cell permeable: no', 'Primary Target
A fluorogenic substrate for caspase-6 (Mch2', 'Product does not compete with ATP.', 'Reversible: no | | References | [1] Vikas Kaushal, et al. ?Inflammasome-mediated activation of caspase-1 and caspase-6 in primary human neurons.Volume8,?Issue4S_Part_8.Alzheimer 's Association International Conference 2012. |
| | Z-VEID-AFC Preparation Products And Raw materials |
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