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| | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol Basic information | | Reactions |
| Product Name: | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol | | Synonyms: | RACEMIC-6,6'-DIBROMO-1,1'-BI-2-NAPHTHOL;(S)-(+)-6'-DIBROMO-1,1'-BI-2-NAPHTHOL;(S)-(+)-6,6'-DIBROMO-2,2'-DIHYDROXY-1,1'-BINAPHTHYL;(S)-(+)-6,6'-DIBROM-2,2'-DIHYDROXY-1,1'-BINAPHTHYL;(S)-(-)-6,6'-DIBROMO-1,1'-BI-2-NAPHTHOL;(S)-(+)-6,6'-DIBROMO-1,1'-BI-2-NAPHTHOL;(S)-6,6'-DIBROMO-1,1'-BI-2-NAPHTHOL;(S)-(+)-6,6'-DIBROMO-1,1'-BI-NAPHTHOL | | CAS: | 80655-81-8 | | MF: | C20H12Br2O2 | | MW: | 444.12 | | EINECS: | 632-860-3 | | Product Categories: | BINOL Series;Chiral Oxygen;Asymmetric Synthesis;Synthetic Organic Chemistry;chiral;blocks;Bromides;Privileged Ligands and Complexes;BINOLs;Chiral Catalysts, Ligands, and Reagents | | Mol File: | 80655-81-8.mol |  |
| | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol Chemical Properties |
| Melting point | 195-199 °C(lit.) | | Boiling point | 546.2±45.0 °C(Predicted) | | density | 1.5428 (rough estimate) | | refractive index | 1.4947 (estimate) | | storage temp. | Inert atmosphere,Room Temperature | | solubility | slightly sol. in Tetrahydrofuran | | form | powder to crystal | | pka | 7.78±0.50(Predicted) | | color | White to Light yellow to Light orange | | optical activity | [α]20/D +49°, c = 1.8 in THF | | CAS DataBase Reference | 80655-81-8(CAS DataBase Reference) |
| | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol Usage And Synthesis |
| Reactions |
- Ligand used to prepare a chiral zirconium catalyst useful in asymmetric Strecker reactions.
- Ligand used in the zinc-catalyzed enantioselective Hetero Diels-Alder reaction.
- Ligand used in asymmetric Friedel-Crafts reactions of pyrroles with glyoxylates.
| | Chemical Properties | white to light yellow crystal powde | | Uses | (S)-(+)-6,6′-Dibromo-1,1′-bi-2-naphthol may be used in the synthesis of (2R,3S)-3-phenylisoserine hydrochloride. It may also be used in the synthesis of BINOL-derived chiral ligands with aryl substituents in the 6,6-positions. [BINOL=1,1′-bi-2-naphthol] | | General Description | (S)-(+)-6,6′-Dibromo-1,1′-bi-2-naphthol is an aromatic chiral Bronsted acid. |
| | (S)-(-)-6,6'-Dibromo-1,1'-bi-2-naphthol Preparation Products And Raw materials |
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