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| | 2-Pyridinecarbaldehyde oxime Basic information |
| | 2-Pyridinecarbaldehyde oxime Chemical Properties |
| Melting point | 110-112 °C(lit.) | | Boiling point | 227.52°C (rough estimate) | | density | 1.2236 (rough estimate) | | vapor pressure | 0.02-0.041Pa at 20-25℃ | | refractive index | 1.4738 (estimate) | | storage temp. | Store below +30°C. | | solubility | methanol: 0.1 g/mL, clear | | form | Solid | | pka | pK1: 3.42(+1);pK2: 10.22(0) (25°C) | | color | Off-White | | Water Solubility | 15 g/L (20 ºC) | | BRN | 109061 | | LogP | 0.3 at 25℃ | | CAS DataBase Reference | 873-69-8(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Pyridinealdoxime(873-69-8) |
| | 2-Pyridinecarbaldehyde oxime Usage And Synthesis |
| Chemical Properties | White powder | | Uses | syn-2-Pyridinealdoxime is a 2-substituted pyridine derivative with inhibitory activity against prolyl-4-hydroxylase. syn-2-Pyridinealdoxime is used in the preparation of DNA-binding silver nitrate complexes. syn-2-Pyridinealdoximeis the N-demethylated analogue of AChE inhibitor Pralidoxime (P701120). | | Purification Methods | Recrystallise it from Et2O/pet ether or H2O. The picrate has m 169-171o (from aqueous EtOH). It is used in peptide synthesis. [UV: Grammaticakis Bull Chem Soc Fr 109, 116 1956, Ginsberg & Wilson J Am Chem Soc 79 481 1957, Hanania & Irvine Nature 183 40 1959, Green & Saville J Chem Soc 3887 1956, Beilstein E-isomer 21 I 288, 21 III/IV 3504, 21/7 V 305.] |
| | 2-Pyridinecarbaldehyde oxime Preparation Products And Raw materials |
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