- 1,6-Dibromohexane
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- $0.00 / 250KG
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2026-04-25
- CAS:629-03-8
- Min. Order: 1KG
- Purity: ≥99%
- Supply Ability: 50 Tons/Month
- 1,6-Dibromohexane
-
- $0.00 / 1KG
-
2026-04-24
- CAS:629-03-8
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
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| | 1,6-Dibromohexane Basic information |
| Product Name: | 1,6-Dibromohexane | | Synonyms: | 1,6-Dibromohexan;1,6-dibromo-hexan;1,6-Dibromohexane,98%;1,6-DibroMohexane, 98% 100ML;1,6-DibroMohexane, 98% 500ML;Hexamethylene Bromide
Hexamethylene Dibromide;1,6-DIBROMOHEXANE FOR SYNTHESIS;alpha,omega-dibromohexane | | CAS: | 629-03-8 | | MF: | C6H12Br2 | | MW: | 243.97 | | EINECS: | 211-067-2 | | Product Categories: | Industrial/Fine Chemicals;DIBROMOALKANE;Bromine Compounds;alpha,omega-Bifunctional Alkanes;alpha,omega-Dibromoalkanes;Monofunctional & alpha,omega-Bifunctional Alkanes;bc0001 | | Mol File: | 629-03-8.mol |  |
| | 1,6-Dibromohexane Chemical Properties |
| Melting point | -2-2.5 °C (lit.) | | Boiling point | 243 °C (lit.) | | density | 1.586 g/mL at 25 °C (lit.) | | vapor pressure | <1 hPa (20 °C) | | refractive index | n20/D 1.507(lit.) | | Fp | 110 °C | | storage temp. | Store below +30°C. | | solubility | soluble in Chloroform, Ethyl Acetate | | form | Liquid | | color | colorless to brownish-yellow | | Water Solubility | insoluble | | BRN | 1236322 | | Dielectric constant | 8.8900000000000006 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | InChI | 1S/C6H12Br2/c7-5-3-1-2-4-6-8/h1-6H2 | | InChIKey | SGRHVVLXEBNBDV-UHFFFAOYSA-N | | SMILES | BrCCCCCCBr | | CAS DataBase Reference | 629-03-8(CAS DataBase Reference) | | NIST Chemistry Reference | Hexane, 1,6-dibromo-(629-03-8) | | EPA Substance Registry System | Hexane, 1,6-dibromo- (629-03-8) |
| Hazard Codes | T,N,C | | Risk Statements | 25-51/53-43 | | Safety Statements | 36-45-61-36/37 | | RIDADR | UN 2810 6.1/PG 3 | | WGK Germany | 3 | | RTECS | MO1515000 | | TSCA | TSCA listed | | HazardClass | 9 | | PackingGroup | III | | HS Code | 29033036 | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Chronic 2
Skin Sens. 1 | | Toxicity | LD50 orally in Rabbit: 1800 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
| | 1,6-Dibromohexane Usage And Synthesis |
| Chemical Properties | colourless or pale yellow liquid. soluble in ethanol, ether, benzene and chloroform, insoluble in water. It is used in the synthesis of the hypotensive drug hexamethonium bromide. | | Uses | 1,6-Dibromohexane is used as a reagent in the synthesis of novel benzo[b]xanthone derivatives which have a potential antitumor activity. It is also used as a cross-linker for the cross-linking of glycuronans. | | Uses | 1,6-Dibromohexane is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are:
Synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications.
Synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.
Synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules.
Synthesis of water-soluble thermoresponsive polylactides. | | Preparation | 1,6-Dibromohexane is synthesized from hexanediol by bromination. | | Synthesis | The general procedure for the synthesis of 1,6-dibromohexane from 1,6-hexanediol was as follows: N-bromosuccinimide (NBS, 534 mg, 3 mmol) was dissolved in dichloromethane (CH2Cl2, 10 mL) in a 50 mL round-bottomed flask. Triphenylphosphine (Ph3P, 786 mg, 3 mmol) and 1,6-hexanediol (1 mmol) were added dropwise to the NBS solution at -78 °C. The reaction mixture was stirred at room temperature away from light for 12 h, during which the progress of the reaction was monitored by thin layer chromatography (TLC, eluent: petroleum ether-ethyl acetate, 20:1). Upon completion of the reaction, the mixture was concentrated under vacuum and purified by fast chromatography on silica gel column (eluent: petroleum ether-ethyl acetate, 30:1) to afford the target product 1,6-dibromohexane. | | References | [1] Synthesis (Germany), 2015, vol. 47, # 8, p. 1154 - 1162
[2] Journal of the American Chemical Society, 1936, vol. 58, p. 488
[3] Archiv der Pharmazie (Weinheim, Germany), 1935, p. 323
[4] Zhurnal Obshchei Khimii, 1935, vol. 5, p. 1508
[5] Journal of the Chemical Society, 1948, p. 46 |
| | 1,6-Dibromohexane Preparation Products And Raw materials |
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