| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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| Products Intro: |
Product Name:Anti-Troponin T antibody, Mouse monoclonal
Purity:monoclonal JLT-12, purified from hybridoma cell culture Package:100μL Remarks:SAB4200717
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| | Anti-Troponin T antibody, Mouse monoclonal Basic information |
| | Anti-Troponin T antibody, Mouse monoclonal Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | Anti-Troponin T antibody, Mouse monoclonal Usage And Synthesis |
| Uses | - Anti-Troponin T antibody, Mouse monoclonal has been used in:
- immunoblotting
- immunofluorescence
- immunohistochemistry
| | General Description | Anti-Troponin T antibody, Mouse monoclonal, (mouse IgG1 isotype) is derived from the JLT-12 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with purified Troponin T from rabbit skeletal muscle. Troponin T (TNNT) is the tropomyosin binding subunit of the troponin complex. Three genes have evolved to encode the cardiac (TNNT2), slow (TNNT1) and fast (TNNT3) skeletal muscle Troponin T proteins, which are specifically expressed in cardial, slow and fast skeletal muscles, respectively. | | Biochem/physiol Actions | Troponin T (TNNT) participates in calcium regulation of actin thin filament function and is required for the contraction of striated muscles. Levels of cardiac Troponin T serve as a sensitive biomarker of myocardial injury. Troponin T has also been suggested as a potential marker in diagnosis of skeletal myopathies including amyotrophic lateral sclerosis (ALS). |
| | Anti-Troponin T antibody, Mouse monoclonal Preparation Products And Raw materials |
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