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(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran

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Company Name: Standardpharm Co. Ltd.
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Products Intro: Product Name:Nebivolol Impurity 23
CAS:197706-51-7
Purity:0.99 Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:Nebivolol A Isomer (Nebivolol Imp-28)
CAS:197706-51-7
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CAS:197706-51-7
Purity:95% HPLC Package:10MG ;25MG;50MG;100MG Remarks:DCTI-C-155
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Products Intro: Product Name:Nebivolol Impurity 10
CAS:197706-51-7
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Products Intro: Product Name:(S)-6-fluoro-2-((R)-oxiran-2-yl)chroman
CAS:197706-51-7
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Basic information
Product Name:(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
Synonyms:(S)-6-fluoro-2-((R)-oxiran-2-yl)chroman;(2S, 2’R)-6-Fluoro-2-(2’-oxiranyl)chromane;2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2S)-;Nebivolol Impurity 10;A-Isomer Nebivolol;Nebivolol A Isomer (Nebivolol Imp-28);Nebivolol Isomer-A
CAS:197706-51-7
MF:C11H11FO2
MW:194.2
EINECS:606-374-7
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Mol File:197706-51-7.mol
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Structure
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Chemical Properties
Boiling point 285.4℃ at 102kPa
density 1.38g/cm3 at 20℃
vapor pressure 0.21-0.4Pa at 20-25℃
form Solid
LogP2.5-3.2 at pH7
Safety Information
MSDS Information
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Usage And Synthesis
Uses(2S,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Preparation Products And Raw materials
Tag:(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran(197706-51-7) Related Product Information
(+-)-(R*,S*)-6-fluoro-3,4-dihydro-alpha-[[(phenylmethyl)amino]methyl]-2H-1-benzopyran-2-methanol Nebivolol Impurity 12 HCl (RR,RR) Defluoro Nebivolol (Mixture of DiastereoMers) Nebivolol Impurity 2 HCl (SR,RS) Didefluoro Nebivolol (Mixture of DiastereoMers) (2R)-rel-6-Fluoro-3,4-dihydro-2-(2R)-2-oxiranyl-2H-1-benzopyran D-Nebivolol,hydrochloride(1:1) Nebivolol Impurity 13 HCl (SS,SS) (2R)-rel-6-Fluoro-3,4-dihydro-2-[(2S)-2-oxiranyl]-2H-1-benzopyran Nebivolol Impurity 28 HCl (SS,RS) 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran Ponazuril (-)-Nebivolol Nebivolol Impurity 10 HCl (RS,SR) 4-Hydroxy Nebivolol, Hydrochloride Hydrate (Mixture of Diastereomers) Nebivolol (R,R,S,R)-Isomer Nebivolol Nebivolol Impurity 3