BRD1652 (BRD 1652)

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BRD1652 (BRD 1652) Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: HANGZHOU CLAP TECHNOLOGY CO.,LTD  
Tel: 86-571-88216897,88216896 13588875226
Email: sales@hzclap.com
Company Name: Wuhan chuang he chemical co. LTD  
Tel: 15907120073
Email: 1261789306@qq.com
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Email: cindy.huang@synzest.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn

BRD1652 (BRD 1652) manufacturers

  • BRD1652
  • BRD1652 pictures
  • $1520.00
  • 2026-07-27
  • CAS:1597438-92-0
  • Purity:
  • Supply Ability: 10g
BRD1652 (BRD 1652) Basic information
Product Name:BRD1652 (BRD 1652)
Synonyms:BRD1652 (BRD 1652);BRD1652;5H-Pyrazolo[3,4-b]quinolin-5-one, 1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-, (4S)-;(4S)-4,7,7-trimethyl-4-phenyl-3-(trifluoromethyl)-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one
CAS:1597438-92-0
MF:C20H20F3N3O
MW:375.39
EINECS:
Product Categories:
Mol File:1597438-92-0.mol
BRD1652 (BRD 1652) Structure
BRD1652 (BRD 1652) Chemical Properties
Safety Information
MSDS Information
BRD1652 (BRD 1652) Usage And Synthesis
DescriptionBRD1652 is a highly selective and potent GSK3 inhibitor. BRD1652 demonstrates in vivo efficacy in a dopaminergic signaling paradigm modeling mood-related disorders. The mood stabilizer lithium, the first-line treatment for bipolar disorder, is hypothesized to exert its effects through direct inhibition of glycogen synthase kinase 3 (GSK3).
UsesBRD1652 is a highly selective GSK3 inhibitor. BRD1652 can be used in the study of emotion-related diseases[1].
in vivo

BRD1652 (30 mg/kg intraperitoneal injection, single dose) can reduce amphetamine-induced hyperactivity disorder (AIH) in mice[1].

References[1] Wagner FF, et al. Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects. ACS Chem Biol. 2016 Jul 15;11(7):1952-63. DOI:10.1021/acschembio.6b00306
BRD1652 (BRD 1652) Preparation Products And Raw materials
Tag:BRD1652 (BRD 1652)(1597438-92-0) Related Product Information
5H-Pyrazolo[3,4-b]quinolin-5-one, 1,4,6,7,8,9-hexahydro-3,7,7-trimethyl-4-(2-pyridinyl)- 5H-Pyrazolo[3,4-b]quinolin-5-one, 1,4,6,7,8,9-hexahydro-3,7,7-trimethyl-4-(4-pyridinyl)- 3,7,7-Trimethyl-4-(4-pyridinyl)-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one 3,7,7-Trimethyl-4-phenyl-1,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one 4-(1,3-Benzodioxol-5-yl)-3,7,7-trimethyl-2,4,6,7,8,9-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one BRD0705