- Rhodamine B
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2026-02-09
- CAS:81-88-9
- Min. Order:
- Purity: 0.99
- Supply Ability:
- Rhodamine B
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- $0.00 / 1KG
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2026-02-09
- CAS:81-88-9
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 30tons/month
- Rhodamine B
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- $33.00 / 100mg
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2026-02-01
- CAS:81-88-9
- Min. Order:
- Purity: 97.53%
- Supply Ability: 10g
Related articles - Applications of Rhodamine B
- Rhodamine B is an organic chloride salt used as a fluorochrome. Rhodamine B has a role as a fluorochrome, a fluorescent probe ....
- Nov 22，2019
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| | Rhodamine B Basic information |
| | Rhodamine B Chemical Properties |
| Melting point | 210-211 (dec.)(lit.) | | density | 0.79 g/mL at 20 °C | | bulk density | 250kg/m3 | | refractive index | 1.6500 (estimate) | | Fp | 12 °C | | storage temp. | room temp | | solubility | H2O: soluble1mg/mL | | Colour Index | 45170 | | form | Solid | | color | Green | | PH | 3-4 (10g/l, H2O, 20℃) | | Water Solubility | SOLUBLE | | ε(extinction coefficient) | 104500-115800 at 542-554nm in methanol | | Merck | 14,8183 | | BRN | 4119648 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Major Application | cleaning products
cosmetics
food and beverages
personal care | | Cosmetics Ingredients Functions | COLORANT | | InChI | 1S/C28H30N2O3.ClH/c1-5-29(6-2)19-13-15-23-25(17-19)33-26-18-20(30(7-3)8-4)14-16-24(26)27(23)21-11-9-10-12-22(21)28(31)32;/h9-18H,5-8H2,1-4H3;1H | | InChIKey | PYWVYCXTNDRMGF-UHFFFAOYSA-N | | SMILES | [Cl-].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccccc4C(O)=O)=[N+](/CC)CC)c1 | | LogP | 1.9-2 | | CAS DataBase Reference | 81-88-9(CAS DataBase Reference) | | IARC | 3 (Vol. 16, Sup 7) 1987 | | NIST Chemistry Reference | Rhodamine b(81-88-9) | | EPA Substance Registry System | Rhodamine B (81-88-9) |
| | Rhodamine B Usage And Synthesis |
| Description | C.I. Food red 15 is a green crystalline or redviolet powdered solid. Molecular weight =479.1. HazardIdentification (based on NFPA-704 M Rating System):Health 1, Flammability 1, Reactivity 0. Highly soluble inwater. | | Chemical Properties | red/brown or green crystals | | Chemical Properties | C.I. Food red 15 is a green crystalline or redviolet powdered solid | | Uses | A useful fluorochrome for histology, FRET and mitochondrial probe. | | Uses | Rhodamine B is used in biological studies for an anti-reactive oxygen species/hepatic fibrosis drug delivery system based on salvianolic acid B loaded mesoporous silica nanoparticles. Dyes and metabolites, Environmental Testing. | | Uses | As a dye, especially for paper; as a reagent for antimony, bismuth, cobalt, niobium, gold, manganese, mercury, molybdenum, tantalum, thallium, tungsten; as biological stain. Provisionally listed for use in drugs and cosmetics. | | Definition | ChEBI: An organic chloride salt having N-[9-(2-carboxyphenyl)-6-(diethylamino)-3H-xanthen-3-ylidene]-N-ethylethanaminium as the counterion. An amphoteric dye commonly used as a fluorochrome. | | General Description | Green crystals or reddish-violet powder. Used as a dye, especially for paper, as a metal chelating reagent, and in drugs and cosmetics. | | Air & Water Reactions | Very soluble in water. Solution is bluish-red. Dilute solutions are strongly fluorescent. | | Reactivity Profile | Acidic organic/inorganic salts, such as Rhodamine B, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions. | | Hazard | Questionable carcinogen. | | Synthesis | (1) Phthalic anhydride (15.7 g) and 3-(N,N-dimethylamino) phenol (18.0 g) were added to 1,2-dichlorobenzene (57.0 g). The resulting mixture was stirred at 175 °C for 1 hour and then 3-(N,N-diethylamino) phenol (12.1 g) was added in three batches. After the addition was completed, the reaction mixture was continued to be stirred at 175 °C for 12 hours. After completion of the reaction, the mixture was cooled to below 25°C. Subsequently, 3% aqueous sodium hydroxide solution (100 g) was added and stirred for 30 minutes. After separating the organic layer, 4.5% sulfuric acid (330 g) was added and stirred for 30 minutes. After separation of the aqueous layer, 35% hydrochloric acid (30 g) and sodium chloride (15 g) were added and the mixture was stirred at 80 °C for 1 hour. After cooling to room temperature, the resulting crystals were filtered, washed with 2% hydrochloric acid (300 g) and dried at 80 °C to give the compound of [chemical formula Di] (35 g). | | Potential Exposure | It is used as a color additive in drugs, foods, cosmetics, and fabric dyes. It is also used as a tracing agent in water pollution studies. May be used as an agricultural chemical | | First aid | If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit. | | storage | Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with C.I. Foodred 15 you should be trained on its proper handling andstorage. Store in tightly closed containers in a cool, wellventilated area away from oxidizers and reducing agents.Where possible, automatically pump liquid from drums orother storage containers to process containers. | | Shipping | UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. | | Purification Methods | Major impurities are partially dealkylated compounds not removed by recrystallisation.Purify the dye by chromatography, using ethyl acetate/isopropanol/ammonia (conc)(9:7:4, RF 0.75 on Kieselgel G). It has also been crystallised from a concentrated solution in MeOH by slow addition of dry diethyl ether; or from EtOH containing a drop of conc HCl by slow addition of ten volumes of dry diethyl ether. The solid is washed with ether and air dried. The dried material has also been extracted with *benzene to remove oil-soluble material prior to recrystallisation. Store it in the dark. [Beilstein 18 II 486, 18 III/IV 8246, 19/8 V 669.] | | Properties and Applications |
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TEST ITEMS
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SPECIFICATION
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APPEARANCE
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GREEN GLITTERY CRYSTAL
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SHADE (COMPARE TO STANDARD)
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CLOSE
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WATER SOLUBILITY (60°C)
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8 g/L min
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WATER INSOLUBLE
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0.5% max
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TINTING STRENGTH
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500-505 %
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| | Incompatibilities | Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, strong reducing agents | | References | [1] Patent: US2015/322265, 2015, A1. Location in patent: Paragraph 0064 |
| | Rhodamine B Preparation Products And Raw materials |
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