| Company Name: |
Guangzhou PI PI Biotech Inc
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+86-020-81716320 +86-13602409664 |
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Sales@pipitech.com |
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Product Name:8-Hydroxy Efavirenz
CAS:205754-33-2
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:(4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
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| Company Name: |
Shanghai Devinchem Ltd Gold
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| Tel: |
027-65318838 13646286950 |
| Email: |
sales@devinchem.com |
| Products Intro: |
Product Name:8-HYDROXY EFAVIRENZ
CAS:205754-33-2
Purity:97% Package:1G,5G,10G,100G,1KG Remarks:CL2379
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:8-Hydroxy Efavirenz
CAS:205754-33-2
Package:100Mg,25Mg,50Mg
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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| Tel: |
021-50135380 |
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shchemsky@sina.com |
| Products Intro: |
Product Name:rac 8-Hydroxy Efavirenz-d4;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoroMethyl)-2H-3,1-benzoxazin-2-one; 8-Hydroxyefavirenz
CAS:205754-33-2
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| | RAC 8-HYDROXY EFAVIRENZ Basic information |
| Product Name: | RAC 8-HYDROXY EFAVIRENZ | | Synonyms: | RAC 8-HYDROXY EFAVIRENZ;8-HydroxyEfavirenz;6-Chloro-4-(cyclopropyl-d4-ethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one;(4S)-6-chloro-4-(2-cyclopropylethynyl)-8-hydroxy-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one;Efavirenz Impurity 11(8-Hydroxy Efavirenz);2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)-;8-Hydroxy EfavirenzQ: What is
8-Hydroxy Efavirenz Q: What is the CAS Number of
8-Hydroxy Efavirenz Q: What is the storage condition of
8-Hydroxy Efavirenz Q: What are the applications of
8-Hydroxy Efavirenz;2H-3,1-Benzoxazin-2-one,6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-8-hydroxy-4-(trifluoromethyl)-, (4S)- | | CAS: | 205754-33-2 | | MF: | C14H9ClF3NO3 | | MW: | 331.67 | | EINECS: | | | Product Categories: | Metabolites;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Intermediates & Fine Chemicals;Isotope Labeled Compounds | | Mol File: | 205754-33-2.mol |  |
| | RAC 8-HYDROXY EFAVIRENZ Chemical Properties |
| Melting point | 144-154°C | | Boiling point | 373.6±42.0 °C(Predicted) | | density | 1?+-.0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Acetonitrile: soluble; DMSO: soluble; Methanol: soluble | | form | A solid | | pka | 7.18±0.40(Predicted) |
| | RAC 8-HYDROXY EFAVIRENZ Usage And Synthesis |
| Description | 8-hydroxy Efavirenz is a major oxidative metabolite of the non-nucleoside reverse transcriptase inhibitor efavirenz . 8-hydroxy Efavirenz is formed when efavirenz is metabolized by the cytochrome P450 (CYP) isoform CYP2B6. It induces apoptosis in rat primary hippocampal neurons and loss of dendritic spines in rat primary hippocampal neuronal cultures when used at a concentration of 0.01 μM. | | Chemical Properties | Off-White Solid | | Uses | 8-Hydroxy Efavirenz is a metabolite of Efavirenz (E425000), a nonnucleoside HIV-1 reverse transcriptase inhibitor. | | Uses | A labellebed metabolite of Efavirenz, a nonnucleoside HIV-1 reverse transcriptase inhibitor |
| | RAC 8-HYDROXY EFAVIRENZ Preparation Products And Raw materials |
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