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DC Chemicals
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Product Name:GLS1 Inhibitor CAS:1832646-52-2 Purity:98% HPLC Package:100mg,250mg,1g
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:GLS1 Inhibitor CAS:1832646-52-2 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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TargetMol Chemicals Inc.
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Product Name:GLS1 Inhibitor;GLS1 Inhibitor,GLS-1 Inhibitor CAS:1832646-52-2 Purity:98% Package:200 mg
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Nanjing Tengyi Biotechnology Co., Ltd
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Product Name:αS-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1,3,4-thiadiazol-2-yl]-benzeneacetamide CAS:1832646-52-2 Purity:95+% Package:1g;5g
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Shanghai Yifei Biotechnology Co. , Ltd.
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customer_service@efebio.com |
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Product Name:GLS1 Inhibitor CAS:1832646-52-2 Purity:98% Package:1mg;5mg;10mg
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| GLS1 Inhibitor Basic information |
Product Name: | GLS1 Inhibitor | Synonyms: | 4-thiadiazol-2-yl]-benzeneacetamide;αS-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1;ΑS-METHOXY-N-[5-[[(3R)-1-(3-PYRIDAZINYL)-3-PYRROLIDINYL]AMINO]-1;3;4-THIADIAZOL-2-YL]-BENZENEACETAMIDE;Benzeneacetamide, α-methoxy-N-[5-[[(3R)-1-(3-pyridazinyl)-3-pyrrolidinyl]amino]-1,3,4-thiadiazol-2-yl]-, (αS)-;GLS1 Inhibitor,GLS-1 Inhibitor | CAS: | 1832646-52-2 | MF: | C19H21N7O2S | MW: | 411.48 | EINECS: | | Product Categories: | | Mol File: | 1832646-52-2.mol | |
| GLS1 Inhibitor Chemical Properties |
density | 1.425±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml | form | A crystalline solid | pka | 7.42±0.50(Predicted) |
| GLS1 Inhibitor Usage And Synthesis |
Description | GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50 = 0.021 μM). It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cells in vitro (GI50 = 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model. |
| GLS1 Inhibitor Preparation Products And Raw materials |
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