Methotrexate α-tert-Butyl Ester

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Company Name: Nantong QuanYi Biotechnology Co., Ltd  Gold
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Products Intro: Product Name:Methotrexate α-tert-Butyl Ester
CAS:79640-70-3
Purity:98% HPLC Package:5mg,25mg,100mg,250mg,1g,5g,10g
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Products Intro: Product Name:(S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid
CAS:79640-70-3
Purity:95% Package:5mg;25mg;100mg;500mg;1g;5g;10g;25g;50g;100g;250g;500g;kg…
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Products Intro: Product Name:Methotrexate α-tert-Butyl Ester
CAS:79640-70-3
Purity:95%, 97%, 98% Package:1g;5g;100g
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
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Products Intro: Product Name:Methotrexate α-tert-butyl ester
CAS:79640-70-3
Purity:95% Package:5mg;10mg;25mg;50mg
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Products Intro: Product Name:Methotrexate α-tert-Butyl Ester
CAS:79640-70-3
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Methotrexate α-tert-Butyl Ester Basic information
Product Name:Methotrexate α-tert-Butyl Ester
Synonyms:Methotrexate α-tert-Butyl Ester;(S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid;L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) ester;Methotrexate a-tert-Butyl Ester;Methotrexate α-tert-Butyl Ester;Methotrexate Impurity 8
CAS:79640-70-3
MF:C24H30N8O5
MW:510.55
EINECS:
Product Categories:
Mol File:79640-70-3.mol
Methotrexate α-tert-Butyl Ester Structure
Methotrexate α-tert-Butyl Ester Chemical Properties
Melting point >211°C (dec.)
density 1.377±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka4.43±0.10(Predicted)
color Pale Yellow to Orange
Safety Information
MSDS Information
Methotrexate α-tert-Butyl Ester Usage And Synthesis
UsesMethotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.
Methotrexate α-tert-Butyl Ester Preparation Products And Raw materials
Raw materialsH-Glu(OMe)-OtBu-->4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID-->L-Glutamic acid α-tert·butyl ester
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