N-(Trimethylsilyl)acetamide

N-(Trimethylsilyl)acetamide Suppliers list

Company Name:	Hubei Changfu Chemical Co., Ltd.
Tel:	+86-02784396550 +86-17721064038
Email:	sales@cfsilanes.com
Products Intro:	Product Name:N-Trimethylsilylacetamide CAS:13435-12-6 Purity:97% Package:1kg;0.00;USD

Company Name:	Shanghai Daken Advanced Materials Co.,Ltd
Tel:	+86-2158073036
Email:	info@dakenam.com
Products Intro:	Product Name:N-(Trimethylsilyl)acetamide CAS:13435-12-6 Purity:0.99 Package:5KG;1KG

Company Name:	Henan Tianfu Chemical Co.,Ltd.
Tel:	+86-0371-55170693 +86-19937530512
Email:	info@tianfuchem.com
Products Intro:	Product Name:13435-12-6 N-(Trimethylsilyl)acetamide CAS:13435-12-6 Purity:99% Package:25KG;5KG;1KG

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	Product Name:N-(trimethylsilyl)acetamide CAS:13435-12-6 Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG

Company Name:	Win-Win Chemical CO., Limited
Tel:	0086-577-64498589
Email:	sales@win-winchemical.com
Products Intro:	Product Name:N-(trimethylsilyl)acetamide CAS:13435-12-6 Purity:98% Package:10G/ Remarks:pharmaceutical intermediates

N-(Trimethylsilyl)acetamide manufacturers

N-(Trimethylsilyl)acetamide Basic information

Product Name:	N-(Trimethylsilyl)acetamide
Synonyms:	N-(TRIMETHYLSILYL)ACETAMIDE FOR SYNTHESI;N-(Trimethylsilyl)acetamide,97%;N-(Trimethylsilyl);(acetylamino)trimethylsilane;n-(trimethylsilyl)-acetamid;N-TRIMETHYLSILYLACETAMIDE;TRIMETHYLSILYLACETAMIDE;TMSA
CAS:	13435-12-6
MF:	C5H13NOSi
MW:	131.25
EINECS:	236-565-7
Product Categories:	Aliphatics;Miscellaneous Reagents;Analytical Chemistry;GC Derivatizing Reagents;Si (Classes of Silicon Compounds);Silicon Compounds (for Synthesis);Silylacetamides;Silylation (GC Derivatizing Reagents);Si-N Compounds;Synthetic Organic Chemistry;Trimethylsilylation (GC Derivatizing Reagents)
Mol File:	13435-12-6.mol

N-(Trimethylsilyl)acetamide Chemical Properties

Melting point	46-49 °C(lit.)
Boiling point	84 °C18 mm Hg(lit.)
density	0.859±0.06 g/cm3(Predicted)
Fp	135 °F
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, DMSO, Methanol
form	Crystalline Mass
pka	18.23±0.46(Predicted)
color	White to yellow
Water Solubility	reacts
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	741928
Stability:	Moisture Sensitive
CAS DataBase Reference	13435-12-6(CAS DataBase Reference)
EPA Substance Registry System	Acetamide, N-(trimethylsilyl)- (13435-12-6)

Safety Information

MSDS Information

N-(Trimethylsilyl)acetamide Usage And Synthesis

Chemical Properties	WHITE TO YELLOWISH CRYSTALLINE MASS
Uses	N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).
General Description	The efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.
Purification Methods	Distil the amide repeatedly in an inert atmosphere with all operations to be performed in an anhydrous atmosphere. In the presence of moisture, trimethylsilanol (b 31-34o/26mm) is formed and is a likely impurity (check by NMR). [Birkofer et al. Chem Ber 96 1473 1963, Beilstein 4 IV 4011.]

N-(Trimethylsilyl)acetamide Preparation Products And Raw materials

Preparation Products

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