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| | Cetylpyridinium chloride monohydrate Basic information |
| | Cetylpyridinium chloride monohydrate Chemical Properties |
| Melting point | 81-84 °C | | bulk density | 370kg/m3 | | storage temp. | Store below +30°C. | | solubility | H2O: soluble0.5M, clear, colorless to faintly yellow | | form | Powder | | color | White | | PH | 5.0-5.4 (10g/l, H2O, 20℃) | | Water Solubility | Soluble in water, alcohol, chloroform | | Merck | 14,2032 | | BRN | 3578606 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid anhydrides, acid chlorides. | | InChI | InChI=1S/C21H38N.ClH.H2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-19-22-20-17-15-18-21-22;;/h15,17-18,20-21H,2-14,16,19H2,1H3;1H;1H2/q+1;;/p-1 | | InChIKey | NFCRBQADEGXVDL-UHFFFAOYSA-M | | SMILES | C1=[N+](CCCCCCCCCCCCCCCC)C=CC=C1.[Cl-].[H]O[H] | | LogP | 1.699 (est) | | CAS DataBase Reference | 6004-24-6(CAS DataBase Reference) |
| Hazard Codes | T+,N,Xi | | Risk Statements | 25-26-38-50/53-36/37/38 | | Safety Statements | 28-36/37-45-7/9-61-26-36 | | RIDADR | UN 2811 6.1/PG 1 | | WGK Germany | 3 | | RTECS | UU5075000 | | TSCA | Yes | | HazardClass | 6.1 | | PackingGroup | I | | HS Code | 29333999 | | Toxicity | LD50 in rats (mg/kg): 250 s.c.; 6 i.p.; 30 i.v.; 200 orally (Nelson, Lyster) |
| | Cetylpyridinium chloride monohydrate Usage And Synthesis |
| Chemical Properties | white to light beige powder | | Uses | (1-Hexadecyl)pyridinium chloride monohydrate is used in a study to assess removal of emulsified oil from oily waste water and removal of emulsified food and mineral oils from waste water. And it is used for detergent-based extraction of membrane-associated enzymes such as alkaline phosphatase, and in extraction of chromium and palladium. | | Uses | Pharmaceutic aid (preservative). | | Uses | antiinfective (topical) | | Definition | ChEBI: Cetylpyridinium chloride monohydrate is a hydrate. It contains a cetylpyridinium chloride. | | General Description | Cetylpyridinum chloride is a quaternary ammonium compound and an active ingredient of antiseptic oral mouth rinses with broad spectrum antimicrobial activity. Its mode of action involves a rapid bactericidal effect on Gram-positive pathogens and a fungicide effect on certain yeasts.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. | | Purification Methods | Crystallise the chloride from MeOH or EtOH/diethyl ether and dry it in vacuo. [Moss et al. J Am Chem Soc 108 788 1986, Lennox & McClelland J Am Chem Soc 108 3771 1986, Beilstein 20 V 233.] | | Toxics Screening Level | The initial threshold screening level (ITSL) for cetylpyridinium chloride monohydrate is 1.8 μg/m3 based on an annual averaging time. |
| | Cetylpyridinium chloride monohydrate Preparation Products And Raw materials |
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