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Cefmenoxime

Cefmenoxime Suppliers list
Company Name: Guangzhou PI PI Biotech Inc
Tel: ; +8618371201331;+8618371201331
Email: sales@pipitech.com;87478684@qq.com
Products Intro: Product Name:Cefmenoxime
CAS:65085-01-0
Purity:90%+ Package:10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com Remarks:(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Company Name: Shanghai Yingrui Biopharma Co., Ltd.
Tel: +86-21-33585366 E-mail:sales03@shyrchem.com
Email: sales03@shyrchem.com
Products Intro: Product Name:Cefmenoxime
CAS:65085-01-0
Purity:0.98 Package:100g;250g;500g;1kg
Company Name: Hebei Guanlang Biotechnology Co., Ltd.
Tel: +8619930503282
Email: sales3@crovellbio.com
Products Intro: Product Name:Cefmenoxime
CAS:65085-01-0
Purity:99% Package:1PCS;1USD
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Email: sales@conier.com
Products Intro: Product Name:cefmenoxime
CAS:65085-01-0
Purity:0.99 Package:1kg
Company Name: career henan chemical co
Tel: 0086-371-86658258 13203830695
Email: factory@coreychem.com
Products Intro: Product Name: Cefmenoxime
CAS: 65085-01-0
Purity:99% Package:1KG;7USD

Cefmenoxime manufacturers

  • Cefmenoxime
  • $240.00 / KG
  • 2021-10-20
  • CAS:65085-01-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 9000kg/per week
  • Cefmenoxime USP/EP/BP
  • $1.10 / g
  • 2021-07-01
  • CAS:65085-01-0
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons Min
  • Cefmenoxime
  • $205.00 / KG
  • 2020-08-26
  • CAS:65085-01-0
  • Min. Order: 1KG
  • Purity: 99%min
  • Supply Ability: 8000 Kilogram/Kilograms per Month
Cefmenoxime Basic information
Product Name:Cefmenoxime
Synonyms:CEFMENOXIME;(6r-(6alpha,7beta(z)))-7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;(6R,7R)-7-[[(Z)-(2-Aminothiazol-4-yl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;(6R,7R)-7α-[2-(2-Amino-4-thiazolyl)-2-[(Z)-methoxyimino]acetylamino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;7β-[[(Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]cepham-3-ene-4-carboxylic acid;CMX;(6R,7R)-7-[(2E)-2-(2-aMino-1,3-thiazol-4-yl)-2-(MethoxyiMino)acetaMido]-3-{[(1-Methyl-1H-1,2,3,4-tetrazol-5-yl)sulfanyl]Methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(Z)]]-
CAS:65085-01-0
MF:C16H17N9O5S3
MW:511.56
EINECS:278-299-4
Product Categories:Pharmaceutical intermediate
Mol File:65085-01-0.mol
Cefmenoxime Structure
Cefmenoxime Chemical Properties
density 1.96±0.1 g/cm3(Predicted)
pka2.61±0.50(Predicted)
CAS DataBase Reference65085-01-0(CAS DataBase Reference)
Safety Information
MSDS Information
Cefmenoxime Usage And Synthesis
OriginatorTacef,Takeda,W. Germany,1983
UsesAntibacterial.
DefinitionChEBI: A third-generation cephalosporin antibiotic, bearing a 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino group at the 7beta-position and a [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl group at the 3-position.
Manufacturing Process7β-[α-Methoxyimino-α-(2-aminothiazol-4-yl)acetamido]cephalosporanicacid trifluoroacetic acid salt is dissolved in a solution of 272 mg of 1-methyl-5- mercapto-1H-tetrazole, 555 mg of sodium bicarbonate and 68 mg of triethylbenzylammonium bromide in 10 ml of water. The solution is heated at 60°C in nitrogen atmosphere for 6 hours. After cooling, the reaction solution is passed through a column of Amberlite XAD-2 and eluted with water and then with 2.5% ethanol. The procedure yields sodium 7β-[α-methoxyimino-α- (2-aminothiazol-4-yl)acetamido]-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3- cephem-4-carboxylate, MP 174°C to 175°C (decomposition).
Brand nameCefmax (TAP).
Therapeutic FunctionAntibacterial
Antimicrobial activityA semisynthetic cephalosporin supplied as the hydrochloride. Its activity is very similar to that of cefotaxime. A 500 mg intramuscular injection achieves a plasma concentration of 15 mg/L after 40 min. A concentration of 200 mg/L is attained after intravenous administration of 1 g. The plasma half-life is c. 1 h. Around 77% is protein bound. Probenecid increases peak plasma levels and extends the plasma half-life to 1.8 h. Therapeutic concentrations are achieved in CSF. There is a degradation product with a long half-life (around 40 h), but 80–92% of the drug is recovered unchanged from the urine. In patients with renal insufficiency, no significant relation was found between creatinine clearance and peak serum concentrations but there was a linear relationship with plasma half-life and total body clearance. About 10% of the dose appears in the feces, mostly extensively degraded, possibly by the fecal flora.
Toxicity, side effects and clinical use are those common to group 4 cephalosporins.
Tag:Cefmenoxime(65085-01-0) Related Product Information
7-TMCA / for Cefmenoxime, Cefoperazone & Etc. 2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid Ceftizoxime 7-TMCA 4-Thiazoleacetamide 1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl- 2-(2-AMINO-THIAZOL-4-YL)-ACETAMIDE Cefetamet hydrochloride 2-(2-AMINOTHIAZOL-4-YL)ETHYLAMINE Desfuroyl Ceftiofur Cefmenoxime Ceftizoxime sodium 2-(2-Aminothiazol-4-yl)glyoxylic acid Cefotaxime sodium Cefotaxime 2Cefmenoxime·Hydrochloride,CEFMENOXIME HCL,CEFMENOXIME HYDROCHLORIDE 7-(5-amino-5-carboxyvaleramido)cephalosporanic acid Cephalexin