| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
sales8178@energy-chemical.com |
Eschenmoser's salt manufacturers
- ESCHENMOSER'S SALT
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- $1.00
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2024-07-25
- CAS:30354-18-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
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| | Eschenmoser's salt Basic information |
| Product Name: | Eschenmoser's salt | | Synonyms: | N,N-DIMETHYLMETHYLENEAMMONIUM CHLORIDE;N,N-DIMETHYL-METHYLENEIMINIUM CHLORIDE;N,N-dimethylmethyleneammonium bromide;dimethylmethylenammonium chloride;N,N-DIMETHYLMETHYLENEAMMONIUM CHLORIDE, TECH., 90%;Methanaminium, N-methyl-N-methylene-, chloride;N-Methylene-N-methylmethanaminium·chloride;N,N-DIMETHYL-METHYLENEIMINIUM CHLORIDE F | | CAS: | 30354-18-8 | | MF: | C3H8ClN | | MW: | 93.56 | | EINECS: | 250-142-4 | | Product Categories: | | | Mol File: | 30354-18-8.mol |  |
| | Eschenmoser's salt Chemical Properties |
| Melting point | 146-148 °C(lit.) | | Fp | 180 °F | | storage temp. | Store below +30°C. | | solubility | Chloroform (Very Slightly, Heated), DMSO (Sparingly, Heated, Sonicated) | | form | Solid | | color | White to Off-White | | BRN | 505955 | | Stability: | Hygroscopic, Unstable in Protic Solvent | | InChI | 1S/C3H8N.ClH/c1-4(2)3;/h1H2,2-3H3;1H/q+1;/p-1 | | InChIKey | ZJTROANVDZIEGB-UHFFFAOYSA-M | | SMILES | [Cl-].C[N+](C)=C |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | UN 1325 4.1/PG 3 | | WGK Germany | 3 | | F | 3-10-21 | | Storage Class | 4.1B - Flammable solid hazardous materials | | Hazard Classifications | Eye Irrit. 2
Flam. Sol. 2
Skin Irrit. 2
STOT SE 3 |
| | Eschenmoser's salt Usage And Synthesis |
| Uses | N,N-Dimethylmethyleneiminium chloride (Bhme′s salt) is a dimethylaminomethylating agent that can be used as one of the key reagents in the following applications:
- Electrophilic aminomethylation of aldehydes and ketones to synthesize corresponding Mannich products, also known as Mannich reaction.
- Preparation of dihydronaphthyridinones as HIV-1 integrase inhibitors.
- Preparation of cyanotetrahydrooxo-β-carbolines via cyclocondensation of cyanomethyl indole-2-carboxylate with ammonia.
- Asymmetric synthesis of phalarine via stereospecific Pictet-Spengler cyclocondensation and traceless chirality transfer from L-tryptophan.
- Synthesis of functionalized diarylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase-1 (mPGES-1) and 5-lipoxygenase (5-LOX).
- Synthesis of (±)-phalarine with the rearrangement of an azaspiroindolenine and Gassman oxindole preparation as key steps.
| | reaction suitability | reaction type: C-C Bond Formation |
| | Eschenmoser's salt Preparation Products And Raw materials |
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