| Company Name: |
Zhejiang Huida Biotech Co., LTD
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| Tel: |
0571-89903882 18679456698 |
| Email: |
mingxinzhu@huidabiotech.com |
| Products Intro: |
Product Name:Ampullosporin CAS:197960-94-4 Purity:99% HPLC Package:10mg;100mg;1g;10g;100g
|
| Company Name: |
Zhejiang Huida Biotech Co., LTD
|
| Tel: |
0571-0571-89903882 15990081639 |
| Email: |
sunshixuan@huidabiotech.com |
| Products Intro: |
Product Name:Ampullosporin CAS:197960-94-4 Purity:99% HPLC Package:10mg;100mg;1g;10g;100g
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| | L-Glutamamide, N-acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]- Basic information |
| | L-Glutamamide, N-acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]- Chemical Properties |
| | L-Glutamamide, N-acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]- Usage And Synthesis |
| Uses | Ampullosporin A is a peptaibol-type polypeptide that can be isolated from the fungus Sepedonium ampullosporum HKI-0053, exhibiting neuroleptic-like activity. Ampullosporin A can inhibit hyperactivity induced by NMDA receptor antagonist MK-801 (HY-15084B) and ameliorate social behavior abnormalities caused by subchronic drug treatment. Ampullosporin A alters the activity of glutamate receptors without affecting dopamine D1 and D2 receptors[1]. | | References | [1] Berek I, et al. Ampullosporin A, a peptaibol from Sepedonium ampullosporum HKI-0053 with neuroleptic-like activity[J]. Behavioural brain research, 2009, 203(2): 232-239. DOI:10.1016/j.bbr.2009.05.012 |
| | L-Glutamamide, N-acetyl-L-tryptophyl-L-alanyl-2-methylalanyl-2-methylalanyl-L-leucyl-2-methylalanyl-L-glutaminyl-2-methylalanyl-2-methylalanyl-2-methylalanyl-L-glutaminyl-L-leucyl-2-methylalanyl-N1-[(1S)-1-(hydroxymethyl)-3-methylbutyl]- Preparation Products And Raw materials |
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