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Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-

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Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Basic information
Product Name:Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
Synonyms:Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-
CAS:28192-77-0
MF:C32H48O7S
MW:576.79
EINECS:
Product Categories:
Mol File:28192-77-0.mol
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Structure
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Chemical Properties
Boiling point 674.5±55.0 °C(Predicted)
density 1.23±0.1 g/cm3(Predicted)
pka14.51±0.70(Predicted)
Safety Information
MSDS Information
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Usage And Synthesis
UsesMethyl 3-p-Toluenesulfonate-cholic Acid Ester is an intermediate used in the synthesis of Aramchol (A765150), which is a fatty acid conjugate that exhibits hypocholesterolemic effects and studies have shown that aramchol suppresses the activity of stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.
Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)- Preparation Products And Raw materials
Raw materialsCHOLIC ACID METHYL ESTER-->Tosyl chloride
Tag:Cholan-24-oic acid, 7,12-dihydroxy-3-[[(4-methylphenyl)sulfonyl]oxy]-, methyl ester, (3α,5β,7α,12α)-(28192-77-0) Related Product Information