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| (S)-(-)-2-Methyl-1-butanol Basic information |
| (S)-(-)-2-Methyl-1-butanol Chemical Properties |
Melting point | -70 °C | alpha | -5.8 º (neat 23 ºC) | Boiling point | 136-138 °C(lit.) | density | 0.811 g/mL at 25 °C(lit.) | vapor density | 3 (vs air) | vapor pressure | 1 mm Hg ( 13.6 °C) | refractive index | n20/D 1.409(lit.) | Fp | 120 °F | storage temp. | 2-8°C | solubility | soluble in Chloroform, Ethanol | pka | 15.24±0.10(Predicted) | form | clear liquid | color | Colorless to Almost colorless | Odor | ethereal fresh | optical activity | [α]23/D 5.8°, neat | Water Solubility | 36 g/L (30 ºC) | Merck | 14,6030 | BRN | 1718809 | Dielectric constant | 15.8(20℃) | LogP | 1.223 (est) | CAS DataBase Reference | 1565-80-6(CAS DataBase Reference) | NIST Chemistry Reference | 1-Butanol, 2-methyl-, (S)-(1565-80-6) | EPA Substance Registry System | 1-Butanol, 2-methyl-, (2S)- (1565-80-6) |
Hazard Codes | Xn | Risk Statements | 10-20-37-66-2017/10/20 | Safety Statements | 46-24/25 | RIDADR | UN 1105 3/PG 3 | WGK Germany | 1 | RTECS | SB9800000 | HazardClass | 3 | PackingGroup | III | HS Code | 29051990 |
| (S)-(-)-2-Methyl-1-butanol Usage And Synthesis |
Chemical Properties | clear colourless liquid | Uses | (S)-(?)-2-Methylbutanol can be used to prepare:
- (S)-(?)-2-Methyl-1-butyloxy carbonyl amino hexyl isocyanate (MBI), which is used to synthesize isocyanate copolymers.
- Chiral alkoxynaphathoic acid derivatives having liquid crystalline properties.
- 3,4-Bis[(S)-2-methylbutoxy]thiophene, a key intermediate for the synthesis of polythiophenes.
| Uses | (S)-(-)-2-Methylbutanol can be used as a reactant to prepare:
- Methylbutyl-2-(3-thienyl)acetate (MBTA) by esterification reaction with 3-thiophene acetic acid in the presence of an acid catalyst.
- (2S)-2-Methyl-1-butanesulfenyl chloride by reacting with thioacetic acid using Mitsunobu reaction conditions.
- (+)-Violapyrone C and (-)-myxalamide A.
| Definition | ChEBI: The (S)-enantiomer of 2-methylbutan-1-ol. | General Description | rest mainly 3-methyl-1-butanol | Purification Methods | Reflux the butanol with CaO, distil, reflux with magnesium and again fractionally distil it. A small sample of highly purified material is obtained by fractional crystallisation after conversion into a suitable ester such as the trinitrophthalate or the 3-nitrophthalate. The latter is converted to the cinchonine salt in acetone and recrystallised from CHCl3 by adding pentane. The salt is saponified, extracted with ether, and fractionally distilled. [Terry et al. J Chem Eng Data 5 403 1960, Beilstein 1 IV 1666.] |
| (S)-(-)-2-Methyl-1-butanol Preparation Products And Raw materials |
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