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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:(S)-Laudanosine
CAS:2688-77-9
Package:10Mg,50Mg
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| Company Name: |
Chemsky (shanghai) International Co.,Ltd
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021-50135380 |
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shchemsky@sina.com |
| Products Intro: |
Product Name:(S)-Laudanosine;(1S)-
CAS:2688-77-9
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
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| Company Name: |
ChemStrong Scientific Co.,Ltd
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0755-0755-66853366 13670046396 |
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sales@chem-strong.com |
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Product Name:Cisatracurium Besylate Impurity 49;(S)-Laudanosine
CAS:2688-77-9
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| Company Name: |
Shanghai Xiang Xin Industrial Co., Ltd.
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| Tel: |
021-50211651 13651607026 |
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sales@xxgmpharm.com |
| Products Intro: |
Product Name:(S)-Laudanosine
CAS:2688-77-9
Purity:99% Package:25mg/;50mg/;100mg/
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| | laudanosine Basic information |
| Product Name: | laudanosine | | Synonyms: | Nsc 35045;(+)-(S)-Laudanosine;(1S)-1,2,3,4-Tetrahydro-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methylisoquinoline;[1S,(+)]-1-[(3,4-Dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinoline;Einecs 220-253-2;Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (1S)-;(S)-1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline;Cisatracurium Besylate Impurity 49 | | CAS: | 2688-77-9 | | MF: | C21H27NO4 | | MW: | 357.44 | | EINECS: | 220-253-2 | | Product Categories: | Alkaloids;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Aromatics, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 2688-77-9.mol |  |
| | laudanosine Chemical Properties |
| Melting point | 89° | | alpha | D16 +106° (c = 1.6 in 97% alc); D16 +130° (chloroform); D22 +52.2 ±1.3° (chloroform); D20 +82.5° (ethanol) | | Boiling point | 490.07°C (rough estimate) | | density | 1.1729 (rough estimate) | | refractive index | 1.5614 (estimate) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated) | | form | White to Pale Beige | | pka | 7.80±0.40(Predicted) |
| | laudanosine Usage And Synthesis |
| Uses | Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity. | | Definition | ChEBI: Laudanosine is a member of isoquinolines. | | Purification Methods | Crystallise these from EtOH. The (±)-picrate crystallises from EtOH with m 177-178o. The (-)-isomer has m 83-85o and |
| | laudanosine Preparation Products And Raw materials |
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