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| | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Basic information |
| Product Name: | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol | | Synonyms: | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol;2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- (9CI);1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol;rac Penbutolol-d9;rac Penbutolol;Penbutolol Solution, 100ppm;PenbutololQ: What is
Penbutolol Q: What is the CAS Number of
Penbutolol Q: What is the storage condition of
Penbutolol;2-Propanol, 1-(2-cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]- | | CAS: | 36507-48-9 | | MF: | C18H29NO2 | | MW: | 291.42836 | | EINECS: | 2530743 | | Product Categories: | | | Mol File: | 36507-48-9.mol |  |
| | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Chemical Properties |
| Melting point | 55-75°C | | Boiling point | 438.2±40.0 °C(Predicted) | | density | 1.030±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Acetone (Slightly), Chloroform (Slightly), Methanol | | form | Solid | | pka | 13.90±0.20(Predicted) | | color | White to Off-White |
| | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Usage And Synthesis |
| Chemical Properties | White to Off-White Solid | | Uses | Labelled Penbutolol (P220500). A β-adrenoceptor antagonist. Antihypertensive. | | Enzyme inhibitor | This non-selective antihypertensive b-blocker (FW = 291.43 g/mol; CAS 36507-48-9; IUPAC: (S)-1-(tert-butylamino)-3-(2-cyclopentylphenoxy)- propan-2-ol), known variously as Levatol, Levatolol, Lobeta, Paginol, Hostabloc, and Betapressin, binds to both b1- and b2-adrenergic receptors, thus exhibiting the sympathomimetic effects of a partial b-adrenergic agonist, while also acting as a serotonin (5-HT1A) receptor antagonist. By blocking b-adrenergic receptors and the sympathetic nervous system, penbutolol decreases heart rate and cardiac output, thereby lowering arterial blood pressure. | | IC 50 | Beta-1 adrenergic receptor |
| | 1-(tert-butylamino)-3-(o-cyclopentylphenoxy)propan-2-ol Preparation Products And Raw materials |
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