ethiazide

ethiazide Suppliers list
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Products Intro: Product Name:ethiazide
CAS:1824-58-4
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CAS:1824-58-4
Purity:98%HPLC Package:1kg;5kg;10kg
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Products Intro: Product Name:7-Chloro-2-ethyl-4,4-dioxo-1,2,3-trihydro-4-thiaquinazoline-6-sulfonamide
CAS:1824-58-4
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ethiazide Basic information
Product Name:ethiazide
Synonyms:6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;Eclotizide;Etizide;Neo Diuresal;Salta;6-chloro-3-ethyl-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;ethiazide
CAS:1824-58-4
MF:C9H12ClN3O4S2
MW:325.79
EINECS:217-358-0
Product Categories:
Mol File:1824-58-4.mol
ethiazide Structure
ethiazide Chemical Properties
Melting point 269-270°
Safety Information
MSDS Information
ethiazide Usage And Synthesis
OriginatorEthiazide,Tokyo Tanabe,Japan,1970
Manufacturing ProcessA mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure; on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3- ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C.
Therapeutic FunctionDiuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant
ethiazide Preparation Products And Raw materials
Raw materialsPropionaldehyde-->Isothiazolinones-->4-Amino-6-chlorobenzene-1,3-disulfonamide
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