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1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-

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1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Suppliers list
Company Name: Aladdin Scientific
Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:HPK1-IN-8
CAS:1214561-09-7
Purity:98% Package:$750.9/1mg;$2400.9/5mg;Bulk package Remarks:98%
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Basic information
Product Name:1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-
Synonyms:1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-;HPK1-IN-8
CAS:1214561-09-7
MF:C19H17FN6O2S
MW:412.44
EINECS:
Product Categories:
Mol File:1214561-09-7.mol
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Structure
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Chemical Properties
density 1.53±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka8.27±0.50(Predicted)
Safety Information
MSDS Information
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Usage And Synthesis
Biological ActivityHPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1.
References[1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124.
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Preparation Products And Raw materials
Tag:1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-(1214561-09-7) Related Product Information