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2-Acetylbutyrolactone Suppliers list
Company Name: Henan DaKen Chemical CO.,LTD.
Tel: +86-371-55531817
Products Intro: Product Name:2-Acetylbutyrolactone
Purity:99.00% Package:100g,500g,1KG,10KG,100KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: 0371-55170693
Products Intro: CAS:517-23-7
Purity:99% Package:500G;1KG;5KG;25KG
Company Name: Hefei TNJ Chemical Industry Co.,Ltd.
Tel: 86-0551-65418684 18949823763
Products Intro: Product Name:2-Acetylbutyrolactone
Purity:99.9%min. Package:1KG;6USD
Company Name: Hebei Chisure Biotechnology Co., Ltd.
Tel: +8613292890173
Products Intro: Product Name:2-Acetylbutyrolactone
Purity:99% Package:1KG;10USD
Company Name: career henan chemical co
Tel: +86-371-86658258
Products Intro: Product Name:2-Acetylbutyrolactone
Purity:99% Package:1kg;2USD

Lastest Price from 2-Acetylbutyrolactone manufacturers

  • 2-Acetylbutyrolactone
  • US $2.00 / kg
  • 2019-07-06
  • CAS:517-23-7
  • Min. Order: 10kg
  • Purity: 99%
  • Supply Ability: ask
  • 2-Acetylbutyrolactone
  • US $10.00 / KG
  • 2019-05-06
  • CAS:517-23-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500tons/month
  • 2-Acetylbutyrolactone
  • US $6.00 / KG
  • 2018-04-04
  • CAS:517-23-7
  • Min. Order: 200KG
  • Purity: 99.9%min.
  • Supply Ability: 10000 tons per year
2-Acetylbutyrolactone Basic information
Description Reference
Product Name:2-Acetylbutyrolactone
Synonyms:2-Acetylbutyrolacton 3-Acetyl-dihydro-2(3H)-furanone;-(-2-Hydroxyethyl)acetoaceticacid-lactone;3-Acetyl-2-(3H)-4,-5-dihydrofuranone;2-Acetyl-4-hydroxybutyric acid gamma-lactone;2-Acetylbutyrolacton;2-Oxo-3-acetyltetrahydrofuran;3-Acetyl-2(3H)-4,5-dihydrofuranone;3-acetyldihydro-2(3h)-furanon
Product Categories:ketone;Furan&Benzofuran;Carbonyl Compounds;Lactones;Organic Building Blocks;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Organic solvents
Mol File:517-23-7.mol
2-Acetylbutyrolactone Structure
2-Acetylbutyrolactone Chemical Properties
Melting point <25 °C
Boiling point 107-108 °C5 mm Hg(lit.)
density 1.19 g/mL at 25 °C(lit.)
refractive index n20/D 1.459(lit.)
Fp >230 °F
storage temp. -20?C Freezer, Under Inert Atmosphere
solubility 200g/l
form Liquid
color Clear
Water Solubility 310 g/L (20 ºC)
Merck 14,83
BRN 112676
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference517-23-7(CAS DataBase Reference)
NIST Chemistry Reference2(3H)-Furanone, 3-acetyldihydro-(517-23-7)
EPA Substance Registry System2(3H)-Furanone, 3-acetyldihydro- (517-23-7)
Safety Information
Hazard Codes Xi,T
Risk Statements 36/37/38-61
Safety Statements 26-36-37/39-45-53
WGK Germany 1
RTECS LU3456000
HS Code 29322980
MSDS Information
ABL English
SigmaAldrich English
ACROS English
ALFA English
2-Acetylbutyrolactone Usage And Synthesis
DescriptionIt is an important intermediate involved in the synthesis of chemical and pharmaceutical products such as vitamin B, 3,4-substituted pyridine, 5-(2-Hydroxyethyl)-4-methylthiazole. In presence of 2-acetylbutyrolactone, reaction of tert-butyl isocyanide with dialkyl acetylenedicarboxylates leads to the formation of dialkyl (E)-2-{(tert-butylamino)[2-oxo-4,5-dihydro-3(2H)-furanylidene]methyl}-2-butenedioates.1 Moreover, reaction of 2-acetylbutyrolactone with thiosemicarbazide and 3-(2-bromo-acetyl)-chromen-2-one in anhydrous ethanol produced 3-{2-[5-hydroxyl-4-(2-hydroxyl-ethyl)-3-methyl-pyrazol-1-yl]-thiazol-4-yl}-chromen-2-one in good yields.2 In addition, 2-acetylbutyrolactone can also function as the raw material for synthesizing pilocarpine that is a leading therapeutic agent for the treatment of narrow and wide angle glaucoma.3 Besides, this chemical can also act as a fluorogenic reagent in the quantitative spectrofluorometric determination of primary amines, which has been demonstrated to be equally accurate and precise as the officially or other reported methods.4
  1. Asghari, S.; Mohammadi, L., Reaction of tert-butyl isocyanide and dialkyl acetylenedicarboxylates in the presence of 2-acetylbutyrolactone. Synthesis of functionalized alpha-methylene-gamma-butyrolactones. Tetrahedron Lett. 2006, 47, 4297-4299.
  2. Rao, V. R.; Kumar, P. V., Facile one-pot synthesis of 3-{25-hydroxy-4-(2-hydroxy-ethyl)-3-methyl-pyrazol-1-yl -thiazol-4-yl} -chromen-2-ones via a three-component reaction. Synth. Commun. 2006, 36, 2157-2161.
  3. Horne, D. A.; Fugmann, B.; Yakushijin, K.; Buchi, G., A SYNTHESIS OF PILOCARPINE. J. Org. Chem. 1993, 58, 62-64.
  4. Sabry, S. M., Application of 2-acetylbutyrolactone to spectrofluorinietry: Fluorescence properties of Schiff bases derived from 2-acetylbutyrolactone and spectrofluorimetric determination of primary amine-containing compounds. J. Pharm. Biomed. Anal. 2006, 40, 1057-1067.
Chemical PropertiesColorless to light yellow liqui
UsesAn intermediate in the synthesis of 2,4-disubstituted pyridines. A fluorogenic reagent for the spectrofluorimetric determination of primary amines.
UsesIn synthesis of 3,4-disubstituted pyridines; of 5-(b-hydroxethyl)-4-methylthiazole.
Tag:2-Acetylbutyrolactone(517-23-7) Related Product Information
A-TRIFLUOROACETYL-G-BUTYROLACTONE, HYDRATE butalactin 3-ACETYL-3-CHLORO-DIHYDRO-FURAN-2-ONE Dihydro-3-(3-pyridoyl)-2-(3H)-furanone tetronomycin OXO-(2-OXO-TETRAHYDRO-FURAN-3-YL)-ACETIC ACID ETHYL ESTER A-TRIFLUOROACETYL-G-BUTYROLACTONE A-DIFLUOROACETYL-G-BUTYROLACTONE okilactomycin 2-Acetylbutyrolactone Acetyl coenzyme A sodium salt Acetyl-resveratrol c-Abl Acetyl chloride tributyl acetocitrate 2,6-Dimethyl-7-octen-2-ol Acetylacetone Gamma-butyrolactone(GBL)