| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
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3bsc@sina.com |
| Products Intro: |
Product Name:Ch 55;4-[(1E)-3-[3,5-bis(1,1-DiMethylethyl)phenyl]-3-oxo-1-propenyl]benzoicacid
CAS:110368-33-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:Ch 55
CAS:110368-33-7
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:CH 55
CAS:110368-33-7
Purity:≥98% by HPLC
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| Product Name: | CH 55 | | Synonyms: | CH 55;4-[(1E)-3-[3,5-BIS(1,1-DIMETHYLETHYL)PHENYL]-3-OXO-1-PROPENYL]BENZOIC ACID;4-[(E)-3-(3,5-Di-tert-butylphenyl)-3-oxo-1-propenyl]benzoic acid;4-[(E)-3-[3,5-Bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid;4-[(E)-3-[3,5-Bis(tert-butyl)phenyl]-3-oxo-1-propenyl]benzoic acid;(E)-4-(3-(3,5-Bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)benzoic acid;Benzoic acid, 4-(3-(3,5-bis(1,1-dimethylethyl)phenyl)-3-oxo-1-propenyl)-, (E)-;Benzoic acid, 4-[(1E)-3-[3,5-bis(1,1-dimethylethyl)phenyl]-3-oxo-1-propen-1-yl]- | | CAS: | 110368-33-7 | | MF: | C24H28O3 | | MW: | 364.48 | | EINECS: | | | Product Categories: | Intracellular receptor | | Mol File: | 110368-33-7.mol |  |
| | CH 55 Chemical Properties |
| Melting point | 202-203.5 °C | | Boiling point | 509.5±50.0 °C(Predicted) | | density | 1.085±0.06 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; DMSO:PBS (pH 7.2) (1:4): 0.2 mg/ml; Ethanol: 5 mg/ml | | form | A crystalline solid | | pka | 4.09±0.10(Predicted) | | Stability: | Light Sensitive |
| | CH 55 Usage And Synthesis |
| Uses | CH 55 is a synthetic analog of retinoic acid which is an effective inhibitor of angiogenesis. Retinoids and their analogs are also promising agents for cancer chemoprevention and therapy. | | Definition | ChEBI: 4-[3-(3,5-ditert-butylphenyl)-3-oxoprop-1-enyl]benzoic acid is a member of chalcones. | | Biological Activity | Highly potent synthetic retinoid that has high affinity for RAR- α and RAR- β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC 50 values are 0.02 and 0.03 nM respectively). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC 50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC 50 = 1 nM). | | storage | Store at RT |
| | CH 55 Preparation Products And Raw materials |
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