Company Name: |
Affinity(Wuhan)Ltd.
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Tel: |
15841022315 |
Email: |
sales@affinitytech.cn |
Products Intro: |
Product Name:Ac-Lys(Fmoc)-Val-Cit-PAB CAS:1609108-48-6 Purity:>96% Package:100mg;1g;10g
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Company Name: |
TargetMol Chemicals Inc.
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Tel: |
15002134094 |
Email: |
marketing@targetmol.cn |
Products Intro: |
Product Name:AcLys-PABC-VC-Aur0101 intermediate-1 CAS:1609108-48-6 Package:50mg/RMB 13800
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| L-Ornithinamide, N2-acetyl-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- Basic information |
| L-Ornithinamide, N2-acetyl-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- Chemical Properties |
Boiling point | 1121.4±65.0 °C(Predicted) | density | 1.254±0.06 g/cm3(Predicted) | pka | 12.25±0.46(Predicted) |
| L-Ornithinamide, N2-acetyl-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- Usage And Synthesis |
Uses | AcLys-PABC-VC-Aur0101 intermediate-1 is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate[1]. | IC 50 | Cleavable Linker | References | [1] Kenneth John DIRICO, et al. Spliceostatin analogs. WO2014068443A1. |
| L-Ornithinamide, N2-acetyl-N6-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysyl-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- Preparation Products And Raw materials |
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