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Pamidronic acid

Pamidronic acid Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-18871470254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Pamidronic acid
CAS:40391-99-9
Purity:99% Package:5KG;1KG Remarks:C3H11NO7P2
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: 86-18523575427
Email: sales@conier.com
Products Intro: Product Name:Pamidronicacid
CAS:40391-99-9
Purity:99% Package:1kg
Company Name: SIMAGCHEM CORP
Tel: +86 13806087780 13806087780
Email: shaobowang@simagchem.com
Products Intro: Product Name:Pamidronic Acid
CAS:40391-99-9
Purity:0.99 Package:1kg,5kg,25kgs,200kgs;bulk
Company Name: Target Molecule Corp
Tel: 781-999-5354 18019718960
Email: marketing@targetmol.com
Products Intro: Product Name:Pamidronic acid
CAS:40391-99-9
Purity:98.00% Package:5 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Dideu Industries Group Limited
Tel: 029-88380327; 17691182729
Email: Service@dideu.com
Products Intro: Product Name:Pamidronic acid USP/EP/BP
CAS:40391-99-9
Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer

Pamidronic acid manufacturers

  • Pamidronic acid
  • $1.00 / KG
  • 2021-09-29
  • CAS:40391-99-9
  • Min. Order: 1KG
  • Purity: 98%
  • Supply Ability: 10kg/month
Pamidronic acid Basic information
Product Name:Pamidronic acid
Synonyms:PAMIDRONIC ACID;PAMIDRONIC ACID SODIUM SALT;Rescriptor;amidronate;DLV;(3-amino-1-hydroxypropylidene)bisphosphonic acid;(3-Amino-1-hydroxypropylidene)diphosphonic acid;3-AMINO-1-HYDROXY-1,1-PROPANEDIPHOSPHONIC ACID
CAS:40391-99-9
MF:C3H11NO7P2
MW:235.07
EINECS:254-905-2
Product Categories:(intermediate of pamidronate disodium);Delavirdine;API
Mol File:40391-99-9.mol
Pamidronic acid Structure
Pamidronic acid Chemical Properties
Melting point 226-228°C
storage temp. Keep in dark place,Inert atmosphere,2-8°C
Safety Information
MSDS Information
ProviderLanguage
Delavirdine mesylate English
Pamidronic acid Usage And Synthesis
Chemical PropertiesWhite Solid
OriginatorAredia,Novartis,India
Usesanticancer
UsesA biphosphonate bone resorption inhibitor.
Manufacturing ProcessFor a batch size of 5 L, 587.5 g (3.2 moles) of mannitol is dissolved in 3.5 L of water. Pamidronic acid (31.6 g, 0.133 moles) is mixed with a 1.0 L aliquot of the mannitol solution to form a slurry. The slurry is then transferred into the remainder of the mannitol solution, and stirred for at least 15 min. Aqueous 1 N sodium hydroxide (270 ml) is then added and the mixture is stirred until a clear, colorless solution results. The pH is then adjusted to 6.50.1 using either 1 M aqueous phosphoric acid or 1 N aqueous sodium hydroxide, as needed. The solution is then filtered through a 0.22 micron filter, and filled at 20°C into vials at 4.0 ml (4.172 g)/vial, under sterile conditions. The aqueous solution is frozen at -37°C and lyophilized (20 mbar, 20°-40°C) to yield 1,250 vials, each containing 30 mg of amorphous disodium pamidronate. The vials are sealed under positive nitrogen pressure. The disodium pamidronate is amorphous (noncrystalline) by X-ray diffraction and contains 0.7 wt-% water.
Brand nameRescriptor (Agouron).
Therapeutic FunctionBone resorption suppressant
Pamidronic acid Preparation Products And Raw materials
Raw materialsPhosphorus trichloride-->Activated carbon,decolor-->β-Alanine-->Disodium pamidronate-->Sodium hydroxide-->Mannitol
Tag:Pamidronic acid(40391-99-9) Related Product Information
Tetramethyl Ibandronate methyl N-(3-methoxy-3-oxopropyl)-N-methyl-beta-alaninate N-Methylpentylamine b-Alanine, N-methyl-N-pentyl- N-Methyl-N-pentyl-beta-alanine methyl ester Ibandronate Impurity 1(Ibandronate EP Impurity B) (But-3-yn-1-yl)(methyl)amine Ibandronate Impurity 3(Ibandronate EP Impurity C) Trisodium phosphate Acryloyl chloride Phosphonic acid, disodium salt Methyl acrylate Olpadronate Sodium INDEX NAME NOT YET ASSIGNED N-Pentyl-β-alanine INDEX NAME NOT YET ASSIGNED Phosphonic acid, P,P'-[1-hydroxy-3-(methyloxidopentylamino)propylidene]bis- Ibandronate sodium monohydrate