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Sodium thiosulfate pentahydrate

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Products Intro: Product Name:10102-17-7
CAS:10102-17-7
Purity:0.99 Package:25KG,5KG;1KG;500G
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CAS:10102-17-7
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CAS:10102-17-7
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Products Intro: Product Name:sodium thiosulfate pentahydrate
CAS:10102-17-7
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CAS:10102-17-7
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Sodium thiosulfate pentahydrate manufacturers

Sodium thiosulfate pentahydrate Basic information
Product Name:Sodium thiosulfate pentahydrate
Synonyms:SodiuM thiosulfate pentahydra;SodiuM Thiosulfate, 0.100 N Aqueous Solution, USP VoluMetric SolutionAPHA;Sodium thiosulfate pentahydrate 99.999% trace metals basis;Sodium thiosulfate pentahydrate ACS reagent, >=99.5%;Sodium thiosulfate pentahydrate puriss. p.a., ACS reagent, reag. ISO, reag. Ph. Eur., >=99.5%;SODIUM THIOSULFATE PENTAHYDRATE, CRYSTAL LIZED;SODIUM THIOSULF. PENTAHYDRATE FOR PHOT&;SODIUM THIOSULFATE-5-HYDRATE EXTRA PURE,
CAS:10102-17-7
MF:H10Na2O8S2
MW:248.18
EINECS:600-156-5
Product Categories:pharmaceutical intermediates;INORGANIC & ORGANIC CHEMICALS;Inorganics;AlphabeticalBiochemicals and Reagents;Biochemicals and Reagents;Denaturation;Disulfide Bridge Cleavage Reagents;Metal and Ceramic Science;Salts;Sodium Salts;Inorganic Salts;Synthetic Reagents;Mass Spectrometry (MS)&LC-MS;Reagents for Mass Spectrometry (MS);Inorganic Chemicals;Disulfide Bridge Cleavage ReagentsSynthetic Reagents;Spectroscopy;ACS GradeBiochemicals and Reagents;Essential Chemicals;Routine Reagents;Analytical Reagents for General Use;Puriss p.a. ACS;Q-S, Puriss p.a. ACS
Mol File:10102-17-7.mol
Sodium thiosulfate pentahydrate Structure
Sodium thiosulfate pentahydrate Chemical Properties
Melting point 48.5 °C
Boiling point 100 C
density 1.01 g/mL at 25 °C
storage temp. Store at +5°C to +30°C.
solubility H2O: 1 M at 20 °C, clear, colorless
form Solid
color White tranparent
Specific Gravity1.729
OdorOdorless
PH Range6 - 8.5
PH6.0-7.5 (100g/l, H2O, 20℃)
Water Solubility 680 g/L (20 ºC)
Merck 14,8694
Stability:Stable. Incompatible with strong acids, iodine, mercury.
InChIKeyAKHNMLFCWUSKQB-UHFFFAOYSA-L
CAS DataBase Reference10102-17-7(CAS DataBase Reference)
EPA Substance Registry SystemThiosulfuric acid (H2S2O3), disodium salt, pentahydrate (10102-17-7)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 24/25-37/39-36-26
WGK Germany 1
RTECS WE6660000
10
TSCA Yes
HS Code 28323000
ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS Information
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Sodium thiosulfate pentahydrate English
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Sodium thiosulfate pentahydrate Usage And Synthesis
Chemical Propertiestranslucent crystals or white powder
Chemical PropertiesSodium thiosulfate occurs as odorless and colorless crystals, a crystalline powder or granules. It is efflorescent in dry air and deliquescent in moist air.
UsesTitrimetry.
UsesSodium thiosulfate pentahydrate is used as an analytical reagent in laboratories. It is used in photographic processing and in gold extraction. Its alkylated derivatives, S-alkylthiosulfonates, are known as Bunte salts. It is involved in the preparation of thioglycolic acid. Furthermore, it is used to dechlorinate tap water, for removing free bromine from solutions and to check the pH of bleach solutions with liquid indicators. Other uses include tanning of leather; as an active component in hand warmers and chemical heating pads and as an anionic surfactant to aid in the dispersion of pharmaceutical preparations.
Production MethodsOn an industrial scale, sodium thiosulfate is produced chiefly from liquid waste products of sodium sulfide or sulfur dye manufacture. Small-scale synthesis is done by boiling an aqueous solution of sodium sulfite with sulfur.
Brand nameSulfactol (Sterling Winthrop).
Pharmaceutical ApplicationsSodium thiosulfate is used as an antioxidant in pharmaceuticals (ophthalmic, intravenous, and oral preparations). It has also been used for its antifungal properties and as a reagent in analytical chemistry.
SafetySodium thiosulfate is used in ophthalmic, intravenous, and oral pharmaceutical preparations. Apart from osmotic disturbances, sodium thiosulfate is relatively nontoxic. It is moderately toxic by the subcutaneous route and mildly irritating to respiratory tract and skin. Large oral doses have a cathartic action.
LD50 (IP, mouse) 5.6 g/kg
LD50 (IV, mouse) 2.4 g/kg
storageSodium thiosulfate decomposes on heating. The bulk powder should be stored in a cool place, and the container should be kept tightly closed in a dry and well-ventilated place. It should not be stored near acids.
Purification MethodsCrystallise it from EtOH/H2O solutions or from water (0.3mL/g) below 60o by cooling to 0o, and dry it at 35o over P2O5 under vacuum. [Foerster & Mommsen Chem Ber 57 258 1924.] This salt is used as a secondary standard in volumetric analysis [Kilpatrick J Am Chem Soc 45 2132 1923], and is used as “Hypo” in photography [Hargreaves & Dunningham J Soc Chem Ind 42 147T 1923.]
IncompatibilitiesSodium thiosulfate is incompatible with iodine, with acids, and with lead, mercury, and silver salts. It may reduce the activity of some preservatives, including bronopol, phenylmercuric salts, and thimerosal.
Regulatory StatusGRAS listed. Included in the FDA Inactive Ingredients Database (IV solutions; ophthalmic solutions and suspensions; oral capsules, solutions, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Tag:Sodium thiosulfate pentahydrate(10102-17-7) Related Product Information
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