- Ecdysone
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- $0.00 / 1KG
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2024-04-24
- CAS:3604-87-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000
- Ecdysone
-
- $0.00 / 1KG
-
2024-04-24
- CAS:3604-87-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000
- Ecdyterone
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- $0.00 / 20MG
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2024-04-23
- CAS:3604-87-3
- Min. Order: 20MG
- Purity: ≥98% HPLC
- Supply Ability: 1000KG
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| | Ecdysone Basic information |
| Product Name: | Ecdysone | | Synonyms: | 2,3,14,22,25-pentahydroxy-,(2-beta,3-beta,5-beta,22r)-cholest-7-en-6-on;2-beta,3-beta,14,22,25-pentahydroxy-,(20s,22r)-5-beta-cholest-7-en-6-on;ECDYSONE;ECDYSONE, ALPHA-;ALPHA-ECDYSON;ALPHA-ECDYSONE;ALPHA-ECDYSTERONE;7,(5-ALPHA)-CHOLESTEN-2-BETA, 3-BETA, 14-ALPHA, 22R, 25-PENTOL-6-ONE | | CAS: | 3604-87-3 | | MF: | C27H44O6 | | MW: | 464.63 | | EINECS: | 222-760-4 | | Product Categories: | Natural Plant Extract;Steroids | | Mol File: | 3604-87-3.mol |  |
| | Ecdysone Chemical Properties |
| Melting point | 242°C | | alpha | 20578 +62° | | Boiling point | 488.1°C (rough estimate) | | density | 1.0493 (rough estimate) | | refractive index | 1.4482 (estimate) | | storage temp. | 2-8°C | | solubility | Methanol (Very Slightly, Heated) | | pka | 14.07±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Merck | 13,3525 | | BRN | 2422986 | | InChIKey | UPEZCKBFRMILAV-JMZLNJERSA-N | | SMILES | [C@H]1(C[C@@]2([C@](C)(C[C@@H]1O)[C@]1([H])C([C@]3([C@@](CC1)(C)[C@@H]([C@H](C)[C@@H](CCC(C)(C)O)O)CC3)O)=CC2=O)[H])O | | LogP | 0.870 (est) | | CAS DataBase Reference | 3604-87-3(CAS DataBase Reference) |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | FZ8170000 | | F | 10 |
| | Ecdysone Usage And Synthesis |
| Description | ?Ecdysterone, also known as ecdysone or β-ecdysone, is a hormone that regulates the growth and development of insects. In 1954, Butenandt et al. isolated 250mg of the initial insect metamorphic active substance, ecdysone, from 500kg of silkworm pupae. Since then, various similar substances have been isolated from many plants. It has been found that ecdysteroids are not only more abundant in the plant kingdom compared to the animal kingdom, but also widely distributed and abundant in resources. Examples of ferns that contain ecdysteroids include Chinese cornbind, Sichuan cornbind, mulberry leaves, Dectenium heterocarpon, water plantain, Ginkgo biloba, yew, Thelypteris palustris, and Cyrtomium falcatum, among others. | | Uses | α-Ecdysone is a steroidal prohormone. | | Definition | ChEBI: Ecdysone is a 6-oxo steroid that is 5beta-cholest-7-en-6-one substituted by hydroxy groups at positions 2, 3, 14, 22 and 25 respectively (the 2beta, 3beta, 22R stereoisomer). It is a steroid prohormone of the major insect moulting hormone 20-hydroxyecdysone. It has a role as a prohormone. It is a 2beta-hydroxy steroid, a 14alpha-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid, a 6-oxo steroid, a 3beta-sterol and an ecdysteroid. It derives from a hydride of a 5beta-cholestane. | | target | Sodium Channel | ATPase | Potassium Channel | Autophagy | | Metabolic pathway | When white mice are administered 3H-ecdyson,
(2b,3b,14a,22(R),25-pentahydroxy-5b-cholest-7-ene-6-
one) by injection intraperitoneally, ecdysone is
metabolized via hydroxylation at C14, followed by
reduction of ring B into the 6a-hydroxy derivative and
epimerization at C3. | | storage | +4°C | | Purification Methods | Recrystallise -ecdyson from tetrahydrofuran/pet ether and from H2O as a hydrate. It has been purified by chromatogaphy on Al2O3 and elution with EtOAc/MeOH. It has max at 242nm ( 12,400). Its acetate has m 214-216o from EtOAc/pet ether, and the 2,4-dinitrophenylhydrazone has m 170-175o(dec) from EtOAc. [Karlson & Hoffmeister Justus Liebigs Ann Chem 662 1 1963, Karlson Pure Appl Chem 14 75 1967, Beilstein 8 IV 3613.] |
| | Ecdysone Preparation Products And Raw materials |
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