- 3-Nitrophthalic anhydride
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- $62.79 / 25Kg/Drum
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2024-04-23
- CAS:641-70-3
- Min. Order: 25Kg/Drum
- Purity: 98.00%HPLC
- Supply Ability: 8.8tons/month
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| | 3-Nitrophthalic anhydride Basic information |
| Product Name: | 3-Nitrophthalic anhydride | | Synonyms: | 1,3-Isobenzofurandione,4-nitro-;3-Isobenzofurandione,4-nitro-1;NSC 4134;3-Nitrophthalic anhydride, synthesis grade;4-Nitrobenzo[c]furan-1,3-dione, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione;3-Nitrophthalic anhydride,97%;Phthalic anhydride, 3-nitro- (6CI,7CI,8CI);3-Nitrophthalic anhydride 98% | | CAS: | 641-70-3 | | MF: | C8H3NO5 | | MW: | 193.11 | | EINECS: | 211-373-6 | | Product Categories: | Anhydride Monomers;Monomers;Polymer Science;Carbonyl Compounds;Carboxylic Acid Anhydrides;Organic Building Blocks;Building Blocks;Carbonyl Compounds;Carboxylic Acid Anhydrides;Chemical Synthesis;Organic Building Blocks;Amines;Aromatics;Intermediates;Phthalic Acids, Esters and Derivatives;Dyes intermediates | | Mol File: | 641-70-3.mol |  |
| | 3-Nitrophthalic anhydride Chemical Properties |
| | 3-Nitrophthalic anhydride Usage And Synthesis |
| Chemical Properties | Beige to yellow crystalline powder | | Uses | An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones. | | Uses | 4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones. | | Preparation | 3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound. | | Purification Methods | Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.] |
| | 3-Nitrophthalic anhydride Preparation Products And Raw materials |
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