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| | Hydrocortisone Basic information |
| Product Name: | Hydrocortisone | | Synonyms: | [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate;propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester;Hydrocortisonepropylacetate;Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)-;Efficort;Suniderma;hydrocortisone aceponate | | CAS: | 74050-20-7 | | MF: | C26H36O7 | | MW: | 460.56 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;API | | Mol File: | 74050-20-7.mol |  |
| | Hydrocortisone Chemical Properties |
| Melting point | 144-146°C | | density | 1.23±0.1 g/cm3 (20 ºC 760 Torr) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Pale Beige |
| | Hydrocortisone Usage And Synthesis |
| Description | Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate.
Its is reportedly significantly superior to the latter in the treatment of dermatoses of
varying severity. | | Chemical Properties | White to Off-White Solid | | Originator | Beiersdorf (W.Germany) | | Uses | A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid. | | Definition | ChEBI: Hydrocortisone aceponate is a corticosteroid hormone. | | Brand name | Retef |
| | Hydrocortisone Preparation Products And Raw materials |
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