| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
|
| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:CPUL1
CAS:2043660-80-4
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:CPUL1
CAS:2043660-80-4
Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
|
1H-Pyrano[3,2-a]phenazine-2-carbonitrile, 3,5-diamino-1-(3,4-dichlorophenyl)- manufacturers
- CPUL1
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- $1980.00 / 50mg
-
2025-10-27
- CAS:2043660-80-4
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 1H-Pyrano[3,2-a]phenazine-2-carbonitrile, 3,5-diamino-1-(3,4-dichlorophenyl)- Basic information |
| | 1H-Pyrano[3,2-a]phenazine-2-carbonitrile, 3,5-diamino-1-(3,4-dichlorophenyl)- Chemical Properties |
| Boiling point | 711.2±60.0 °C(Predicted) | | density | 1.60±0.1 g/cm3(Predicted) | | pka | 2.40±0.70(Predicted) |
| | 1H-Pyrano[3,2-a]phenazine-2-carbonitrile, 3,5-diamino-1-(3,4-dichlorophenyl)- Usage And Synthesis |
| Uses | CPUL1 is a TrxR inhibitor, which shows proliferation-inhibitory and anti-metastatic activity against A549 cells. CPUL1 influences EMT (epithelial-mesenchymal transition) via inducing ROS-mediated ERK/JNK signaling by inhibiting TrxR1 enzyme activity. CPUL1 in combination with α-Lipoic Acid.html" class="link-product" target="_blank">α-Lipoic Acid (HY-N0492) or Dithiodipropionic acid.html" class="link-product" target="_blank">Dithiodipropionic acid (HY-W014395) is more effective[1]. | | References | [1] Ding Q, et al. A thioredoxin reductase 1 inhibitor pyrano [3,2-a] phenazine inhibits A549 cells proliferation and migration through the induction of reactive oxygen species production. Mol Biol Rep. 2022 Sep;49(9):8835-8845. DOI:10.1007/s11033-022-07733-2 |
| | 1H-Pyrano[3,2-a]phenazine-2-carbonitrile, 3,5-diamino-1-(3,4-dichlorophenyl)- Preparation Products And Raw materials |
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