2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]-

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- Suppliers list

Company Name:	TargetMol Chemicals Inc.
Tel:	+17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:mGlu4 receptor agonist 1 CAS:1678501-16-0 Package:25mg;1520USD\|100mg;2500USD\|50mg;1980USD

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Email:	marketing@targetmol.cn
Products Intro:	Product Name:mGlu4 receptor agonist 1 CAS:1678501-16-0 Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- manufacturers

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- Basic information

Product Name:	2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]-
Synonyms:	2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]-;mGlu4 receptor agonist 1
CAS:	1678501-16-0
MF:	C21H15ClN4O2
MW:	390.82
EINECS:
Product Categories:
Mol File:	1678501-16-0.mol

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- Chemical Properties

density	1.349±0.06 g/cm3(Predicted)
pka	11.06±0.70(Predicted)

Safety Information

MSDS Information

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- Usage And Synthesis

Uses	mGlu4 receptor agonist 1 (compound 62) is a potent mGlu4 receptor positive allosteric modulator, with an EC50 of 308 nM. mGlu4 receptor agonist 1 shows significant anxiolytic- and antipsychotic-like effect[1].
IC 50	mGluR4: 308 ± 35 nM (EC₅₀)
References	[1] Stankiewicz A, et al. New 1,2,4-oxadiazole derivatives with positive mGlu4 receptor modulation activity and antipsychotic-like properties. J Enzyme Inhib Med Chem. 2022 Dec;37(1):211-225. DOI:10.1080/14756366.2021.1998022

2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]- Preparation Products And Raw materials

Tag:2-Pyridinecarboxamide, N-[4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]-3-methylphenyl]-(1678501-16-0) Related Product Information

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