|
|
| | (1R,3S)-Benazepril Hydrochloride Basic information |
| Product Name: | (1R,3S)-Benazepril Hydrochloride | | Synonyms: | 1H-1-Benzazepine-1-acetic acid, 3-[[(1R)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, (3S)-;1H-1-Benzazepine-1-acetic acid, 3-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-, monohydrochloride, [S-(R*,S*)]-;2-((S)-3-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)aceticacidhydrochloride;(1R,3S)-Benazepril Hydrochloride;Benner Pury hydrochloride;Benazepril Related CoMpound B;Benazepril Hydrochloridec;Benazepril USP RC B | | CAS: | 86541-77-7 | | MF: | C24H28N2O5HCl | | MW: | 460.96 | | EINECS: | | | Product Categories: | API intermediates | | Mol File: | 86541-77-7.mol |  |
| | (1R,3S)-Benazepril Hydrochloride Chemical Properties |
| Melting point | 181-183 °C(Solv: 2-butanone (78-93-3)) | | storage temp. | 2-8°C | | form | powder |
| | (1R,3S)-Benazepril Hydrochloride Usage And Synthesis |
| Uses | (1R,3S)-Benazepril Hydrochloride is an isomer of Benazepril (B119750), an angiotensin converting enzyme inhibitor and a antihypertensive agent. | | General Description | Benazepril hydrochloride,(3S)-3-[[(1S)-1-carbethoxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid 3-ethylester hydrochloride (Lotensin), is metabolized rapidly to theactive diacid benazaprilat. As with the ACE prodrugs, nomutagenicity has been found, even though these drugs crossthe placenta. |
| | (1R,3S)-Benazepril Hydrochloride Preparation Products And Raw materials |
|