| Company Name: |
Shanghai meikai technology co., ltd
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| Tel: |
021-68689288 15300790979 |
| Email: |
info@mkbio.com.cn |
| Products Intro: |
Product Name:Cimdelirsensodium(Synonyms:ISIS766720sodium;IONIS-GHR-LRxsodium) CAS:2131025-83-5 Purity:98% Package:100mg;250mg;1g
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| | IONIS-GHR-LRxsodium) Basic information |
| | IONIS-GHR-LRxsodium) Chemical Properties |
| | IONIS-GHR-LRxsodium) Usage And Synthesis |
| Uses | Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients. | | References | [1] Bhanot S, Fleseriu M, Geary R, et al. OR27-4 Placebo-Controlled and Open-Label Extension Study of a Novel Hepatic-Targeted Antisense Cimdelirsen (IONIS-GHR-LRx) Under Investigation in Acromegaly Patients. J Endocr Soc. 2022;6(Suppl 1):A526. |
| | IONIS-GHR-LRxsodium) Preparation Products And Raw materials |
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