- Lupulone
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- $1.00 / 1g
-
2020-01-13
- CAS:468-28-0
- Min. Order: 1g
- Purity: 95-99%
- Supply Ability: 1ton
- LUPULONE
-
- $1.00 / 1g
-
2020-01-13
- CAS:468-28-0
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 200kg
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| | LUPULONE Basic information |
| Product Name: | LUPULONE | | Synonyms: | 2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but;3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc;b’’-acid;lohexadien-1-one;lupulon;LUPULONE;B-LUPULIC ACID;BETA-LUPULIC ACID | | CAS: | 468-28-0 | | MF: | C26H38O4 | | MW: | 414.58 | | EINECS: | 207-405-3 | | Product Categories: | Hop Compounds | | Mol File: | 468-28-0.mol |  |
| | LUPULONE Chemical Properties |
| Melting point | 93℃ | | Boiling point | 453.43°C (rough estimate) | | density | 1.045±0.06 g/cm3 (20 ºC 760 Torr) | | vapor pressure | 0Pa at 20℃ | | refractive index | 1.4840 (estimate) | | storage temp. | Store at -20°C | | solubility | Methanol: slightly soluble | | form | A solid | | pka | 4.50±1.00(Predicted) | | Water Solubility | 1g/L at 20℃ | | Stability: | Hygroscopic | | LogP | 4.5 at 20℃ |
| Hazard Codes | T | | Risk Statements | 25 | | Safety Statements | 45 | | RIDADR | 2811 | | RTECS | OK5950000 | | HazardClass | 6.1(b) | | PackingGroup | III | | Toxicity | LD50 in mice, rats (mg/kg): 525, 100 orally (Hnsel, Wagener) |
| | LUPULONE Usage And Synthesis |
| Uses | Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells. | | Definition | ChEBI: Lupulone is a beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. It has a role as an antimicrobial agent, an apoptosis inducer, an angiogenesis inhibitor and an antineoplastic agent. It is a conjugate acid of a lupulone(1-). | | Purification Methods | Crystallise Lupulon from 90% MeOH, hexane or pet ether at low temperature. It has also been purified by chromatography through Kieselgel. [Wieland et al. Chem Ber 102 2012 1925, Riedl Chem Ber 85 692 1952, Beilstein 7 II 856, 7 III 4752, 7 IV 2866.] |
| | LUPULONE Preparation Products And Raw materials |
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