| Company Name: |
Nantong QuanYi Biotechnology Co., Ltd
|
| Tel: |
0513-66337626 18051384581 |
| Email: |
sales@chemhifuture.com |
| Products Intro: |
Product Name:BMS-986172
CAS:1808258-99-2
Purity:98%+ HPLC Package:10mg，500mg，1g，2g，5g，10g，More
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:BMS-986172
CAS:1808258-99-2
Package:50mg;5mg
|
| Company Name: |
Shanghai Fine Biotech Co.，Ltd
|
| Tel: |
18221172427 |
| Email: |
sale@fine-biotech.com |
| Products Intro: |
Product Name:BMS-986172
CAS:1808258-99-2
Purity:98%HPLC Package:100mg;250mg;1g;5g,10g;25g;100g
|
|
| | BMS-986172 Basic information |
| | BMS-986172 Chemical Properties |
| density | 1.64±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | | form | Solid | | pka | 6.65±0.20(Predicted) | | color | White to off-white |
| | BMS-986172 Usage And Synthesis |
| Uses | BMS-986172 is an orally active, highly selective MGAT2 inhibitor with an IC50 of 4.6 nM and 20 nM for hMGAT2 and mMGAT2, respectively. BMS-986172 has a T1/2>120 min in vitro assays. BMS-986172 reduces food intake and body weight. BMS-986172 has the potential for metabolic disorders such as obesity and NASH research[1]. | | References | [1] Wei Meng, et al. Discovery of 12 (BMS-986172) as a Highly Potent MGAT2 Inhibitor that Achieved Targeted Efficacious Exposures at a Low Human Dose for the Treatment of Metabolic Disorders. J Med Chem. 2023 Sep 28;66(18):13135-13147. DOI:10.1021/acs.jmedchem.3c01147 |
| | BMS-986172 Preparation Products And Raw materials |
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