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L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine

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L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:BE-16627B
CAS:137530-61-1
Purity:0 Package:1mg
Company Name: CHEMICAL LAND21  
Tel: 82- 2 -783 - 8063
Email: sales21@chemicalland21.com
Products Intro:
L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Basic information
Product Name:L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine
Synonyms:L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine;BE-16627B;L-Valine, N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-L-seryl-
CAS:137530-61-1
MF:C16H29N3O7
MW:375.42
EINECS:
Product Categories:
Mol File:137530-61-1.mol
L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Structure
L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Chemical Properties
density 1.243±0.06 g/cm3(Predicted)
pka3.27±0.10(Predicted)
Safety Information
MSDS Information
L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Usage And Synthesis
DescriptionBE-16627B is a novel metalloproteinase (MP) inhibitor isolated from Streptomyces sp. BE16627B selectively inhibited MPs such as human stromelysin and 92 kD gelatinase. After the cells were cultured with BE16627B for 5 days, BE16627B inhibited MP activity in the primary culture supernatants from synovial cells in a dose-dependent fashion without showing apparent cytotoxicity or affecting the production and secretion of MPs. Its IC50 for active collagenolysis before activation by trypsin was 25 microM.
L-N-(N-hydroxy-2-isobutylsuccinamoyl)seryl-L-valine Preparation Products And Raw materials
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