| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:EM 1404
CAS:243836-37-5
Package:50mg;10mg
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| | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)- Basic information |
| Product Name: | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)- | | Synonyms: | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)-;EM 1404 | | CAS: | 243836-37-5 | | MF: | C25H33NO3 | | MW: | 395.54 | | EINECS: | | | Product Categories: | | | Mol File: | 243836-37-5.mol |  |
| | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)- Chemical Properties |
| Boiling point | 558.8±50.0 °C(predicted) | | density | 1.19±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | | pka | 16.30±0.60(predicted) |
| | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)- Usage And Synthesis |
| Uses | EM 1404 is a 17β-HSD5 inhibitor (IC50: 3.2 nM)[1]. | | IC 50 | 17β-HSD5: 3.2 nM (IC50) | | References | [1] Hoffman WE, et al. Cerebrovascular and cerebral metabolic effects of flurazepam and a benzodiazepine antagonist, 3-hydroxymethyl-beta-carboline. Eur J Pharmacol. 1984 Nov 27;106(3):585-91. DOI:10.1016/0014-2999(84)90062-1 |
| | 19,21-Dinorchola-1,3,5(10)-triene-23-carboxylic acid, 3-(aminocarbonyl)-17-hydroxy-23-methyl-, δ-lactone, (17α)- Preparation Products And Raw materials |
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