| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Cathepsin L
Purity:main >= 0.5units/mg protein, solution Package:25μg Remarks:C6854
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| Company Name: |
Shanghai Huzhen Industrial Co., LTD
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| Tel: |
021-60345367 13916550749 |
| Email: |
sales@shzbio.com |
| Products Intro: |
Product Name:Cathepsin L
Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1980;200ul/RMB 2900 Remarks:Cathepsin L heavy chain; Cathepsin L light chain; CathepsinL; CATL; CTSL; CTSL protein; DKFZp686A18159; FLJ31037; Major excreted protein; MEP; cath-L; CL; CATL1_HUMAN; CathepsinL1;
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| Company Name: |
ACROBiosystems
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| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
| Products Intro: |
Product Name:Cathepsin L
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| Company Name: |
ZSGB-BIO
|
| Tel: |
02-400-810-9781 400810978 |
| Email: |
sales@zsbio.com |
| Products Intro: |
Product Name:Cathepsin L
|
| Company Name: |
Merck Millipore
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| Tel: |
1-400-889-1988 400-889-1988 |
| Email: |
bioscience@merckgroup.com |
| Products Intro: |
Product Name:Cathepsin L, Human Liver
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| | CATHEPSIN L Basic information |
| Product Name: | CATHEPSIN L | | Synonyms: | CATHEPSIN L, HUMAN LIVER;CATHEPSIN L (HUMAN);CATHEPSIN L;EC 3.4.22.15;HUMAN CATHEPSIN-L;Magic Red™;Caspases 3&7 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CATHEPSIN L Structure]() |
| | CATHEPSIN L Chemical Properties |
| storage temp. | −20°C | | form | solution | | biological source | human liver |
| Hazard Codes | B | | WGK Germany | 3 |
| | CATHEPSIN L Usage And Synthesis |
| Uses | life science and biopharma | | Biological Activity | Cathepsin L (CTSL) has higher activity than cathepsins B and H in the degradation of a variety of physiological protein substrates. It is believed to be responsible for the generation of endostatin from the NC1 domain in collagen XVII. It is responsible for regulating cell cycle, nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing-3 (NLRP3) inflammasome activation, proteolytic processing of Bid during apoptosis, and TGF-β signaling. It can degrade a wide range of proteins, encompassing enzymes, receptors, and transcription factors. Additionally, it produces active enzymes, receptors, and biologically active peptides through controlled proteolysis. Moreover, Cathepsin L has been observed to enhance tumor cell migration by lowering cell-cell adhesion and breaking down elements of the extracellular matrix. The expression of CTSL escalates in several types of cancers, including glioma, melanoma, pancreatic, prostate, and breast cancer. It plays a major role in the proteolysis of both cellular and endocytosed macromolecules. |
| | CATHEPSIN L Preparation Products And Raw materials |
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