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| | N,N-Dimethylformamide dimethyl acetal Basic information |
| Product Name: | N,N-Dimethylformamide dimethyl acetal | | Synonyms: | Dimethoxy(dimethylamino)methane;N,N-Dimethylfirmanmidedimethylacetal;N,N-Dimethylformamide dimethyl acetal, ca 97%;Methanamine, 1,1-dimethoxy-N,N-dimethyl-;esterate m;n,n-dimethylformamide dimethyl acetal solution;N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL (DMF-DMA);1,1-Dimethoxytrimethylamin | | CAS: | 4637-24-5 | | MF: | C5H13NO2 | | MW: | 119.16 | | EINECS: | 225-063-3 | | Product Categories: | N,N-Dimethylformamide Dialkylacetals (GC Derivatizing Reagents);(intermediate of zaleplon);Aliphatics;blocks;BuildingBlocks;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Protecting Agents for Hydroxyl and Amino Groups;Protecting Agents, Phosphorylating Agents & Condensing Agents;Analytical Chemistry;Esterification & Alkylation (GC Derivatizing Reagents);GC Derivatizing Reagents;4637-24-5;bc0001 | | Mol File: | 4637-24-5.mol |  |
| | N,N-Dimethylformamide dimethyl acetal Chemical Properties |
| Melting point | -85°C | | Boiling point | 102-103 °C/720 mmHg (lit.) | | density | 0.897 g/mL at 25 °C (lit.) | | vapor pressure | 34.5hPa at 20℃ | | refractive index | n20/D 1.396(lit.) | | Fp | 45 °F | | storage temp. | Store below +30°C. | | solubility | Miscible with most organic solvents. | | pka | 5.00±0.50(Predicted) | | form | Solid | | color | White to off-white | | PH | 7 (H2O) | | explosive limit | 1.3-17.7%(V) | | Water Solubility | hydrolysis | | Sensitive | Moisture Sensitive | | BRN | 506020 | | Exposure limits | ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3) | | LogP | 0.750 (est) | | CAS DataBase Reference | 4637-24-5(CAS DataBase Reference) | | NIST Chemistry Reference | Methanamine, 1,1-dimethoxy-N,N-dimethyl-(4637-24-5) | | EPA Substance Registry System | Methanamine, 1,1-dimethoxy-N,N-dimethyl- (4637-24-5) |
| | N,N-Dimethylformamide dimethyl acetal Usage And Synthesis |
| Chemical Properties | clear colourless liquid | | Uses | Used to catalyze the coupling of epoxides with carbon dioxide under solvent free conditions leading to cyclic carbonates. | | Uses | N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates. | | Uses | 1,1-Dimethoxy-N,N-dimethylmethanamine is used as a reagent in the formation of pyridine derivatives that exhibit inhibition against PI3 kinase p110α enzymes. | | Definition | ChEBI: An acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applica
ions | | General Description | Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters. | | Flammability and Explosibility | Highly flammable |
| | N,N-Dimethylformamide dimethyl acetal Preparation Products And Raw materials |
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