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| | 3-aminopiperidine-2,6-dione hydrochloride Basic information |
| Product Name: | 3-aminopiperidine-2,6-dione hydrochloride | | Synonyms: | 3-aminopiperidine-2,6-dione hydrochloride;(+-)-3-Amino-2,6-piperidinedione monohydrochloride;2,6-Piperidinedione, 3-amino-, monohydrochloride, (+-)-;Glutamic acid imide-DL-hydrochloride;3-AMinopiperidine-2,6-Dione-HCL;3-aMino-aza-cyclohexane 2,6-dione hydrochloride;3-aminopiperidine-2;6-dione hydrochloride | | CAS: | 2686-86-4 | | MF: | C5H9ClN2O2 | | MW: | 164.59 | | EINECS: | 806-697-5 | | Product Categories: | | | Mol File: | 2686-86-4.mol |  |
| | 3-aminopiperidine-2,6-dione hydrochloride Chemical Properties |
| Melting point | >208oC (dec.) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly, Heated), Methanol (Sparingly, Sonicated) | | form | Solid | | color | Off-White |
| | 3-aminopiperidine-2,6-dione hydrochloride Usage And Synthesis |
| Description | 3-aminopiperidine-2,6-dione hydrochloride is an important organic synthetic raw material for the preparation of the antineoplastic agent pomalidomide, which is used to treat AIDS-related kaposi's sarcoma in patients who have not responded well to highly active antiretroviral therapy (HAART). It is also used to treat Kaposi's sarcoma in HIV-uninfected (HIV-negative) patients. | | Uses | 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce?ubiquitination and degradation of CK1α in del(5q) MDS.?It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. |
| | 3-aminopiperidine-2,6-dione hydrochloride Preparation Products And Raw materials |
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