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| Ethyl 3,3-Diethoxypropionate Basic information |
Product Name: | Ethyl 3,3-Diethoxypropionate | Synonyms: | Propanoic acid, 3,3-diethoxy-, ethyl ester;3,3-DIETHOXYPROPIONIC ACID ETHYL ESTER;ETHYL 3,3-DIETHOXYPROPIONATE;ETHYL 3,3-DIETHOXYPROPIONATE, TECH., 90%;3,3-Diethoxypropanoic acid, ethyl ester;malonaldehydic acid diethyl acetal ethyl ester;Ethy 3,3-diethoxypropanoate;Ethyl 3,3-diethoxypropionate ,95% | CAS: | 10601-80-6 | MF: | C9H18O4 | MW: | 190.24 | EINECS: | 234-223-1 | Product Categories: | Pyridine;Pharmaceutical Intermediates;bc0001 | Mol File: | 10601-80-6.mol | |
| Ethyl 3,3-Diethoxypropionate Chemical Properties |
Melting point | 200-202 °C | Boiling point | 92-93 °C/13 mmHg (lit.) | density | 0.978 g/mL at 25 °C (lit.) | refractive index | n20/D 1.411(lit.) | Fp | 184 °F | storage temp. | Inert atmosphere,Store in freezer, under -20°C | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Liquid | color | Clear colorless | BRN | 1772110 | Stability: | Hygroscopic | InChI | InChI=1S/C9H18O4/c1-4-11-8(10)7-9(12-5-2)13-6-3/h9H,4-7H2,1-3H3 | InChIKey | SIALOQYKFQEKOG-UHFFFAOYSA-N | SMILES | C(OCC)(=O)CC(OCC)OCC | LogP | 2.260 (est) | CAS DataBase Reference | 10601-80-6(CAS DataBase Reference) |
| Ethyl 3,3-Diethoxypropionate Usage And Synthesis |
Description | Ethyl 3,3-diethoxypropionate is an organic compound that is synthesized from the reaction of diethyl malonate and chloroacetic acid in the presence of a base catalyst. This product has been shown to be an effective inhibitor of mitochondrial cytochrome c oxidase in vitro studies. Ethyl 3,3-diethoxypropionate also has been found to inhibit quinoline derivatives, such as erythromycin and tetracycline, which are involved in bacterial DNA synthesis. Furthermore, this product inhibits β-unsaturated aldehydes and allylation. | Chemical Properties | clear colorless liquid | uses | Ethyl 3,3-diethoxypropionate participates in the Yb(OTf)3 catalyzed synthesis of dihydropyridines (DHPs). | Synthesis Reference(s) | The Journal of Organic Chemistry, 47, p. 2216, 1982 DOI: 10.1021/jo00132a055 Synthesis, p. 274, 1988 DOI: 10.1055/s-1988-27541 |
| Ethyl 3,3-Diethoxypropionate Preparation Products And Raw materials |
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