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| | 2,2,6,6-Tetramethyl-4-piperidinol Basic information |
| Product Name: | 2,2,6,6-Tetramethyl-4-piperidinol | | Synonyms: | TAA-OL;TRIACETONEAMINO ALCOHOL;Tetramethyl piperidylol;2,2,6,6-TETRAMETHYL-4-PIPERIDINOL 99+%;Triacetoneamino Alcohol TAA-ol;4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINE
TAA-OL;2,2,6,6-TetraMethyl-4-piperidinol, 99% 5GR;NSC 16575 | | CAS: | 2403-88-5 | | MF: | C9H19NO | | MW: | 157.25 | | EINECS: | 219-291-2 | | Product Categories: | Chemical intermediate;Aromatics;Heterocycles;Intermediates;Nitric Oxide Reagents;API intermediates;Miscellaneous;Industrial/Fine Chemicals;Nitrogen cyclic compounds;2403-88-5 | | Mol File: | 2403-88-5.mol |  |
| | 2,2,6,6-Tetramethyl-4-piperidinol Chemical Properties |
| Melting point | 129-131 °C(lit.) | | Boiling point | 212-215 °C(lit.) | | density | 1.085 | | refractive index | 1.4248 (estimate) | | Fp | 212-215°C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | methanol: 0.1 g/mL, clear | | pka | 14.99±0.60(Predicted) | | form | Crystals, Crystalline Powder and/or Chunks | | color | White to off-white or slightly beige | | PH | 11.2 (4g/l, H2O, 20℃) | | Water Solubility | 130 g/L (23 ºC) | | BRN | 105039 | | InChIKey | VDVUCLWJZJHFAV-UHFFFAOYSA-N | | CAS DataBase Reference | 2403-88-5(CAS DataBase Reference) | | NIST Chemistry Reference | 4-Piperidinol, 2,2,6,6-tetramethyl-(2403-88-5) | | EPA Substance Registry System | 4-Piperidinol, 2,2,6,6-tetramethyl- (2403-88-5) |
| Hazard Codes | Xi,C | | Risk Statements | 36/37/38-43-34 | | Safety Statements | 26-36-45-36/37/39 | | RIDADR | UN3259 8/PG 2 | | WGK Germany | 1 | | RTECS | TN7871675 | | Hazard Note | Irritant | | TSCA | Yes | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29333999 |
| | 2,2,6,6-Tetramethyl-4-piperidinol Usage And Synthesis |
| Chemical Properties | white to slightly beige crystalline powder | | Uses | 2,2,6,6-tetramethyl-4-piperidinol has been used to study the irradiation of Camptothecin (CPT) in aerated dimethylsulfoxide (DMSO) solution that leads to formation of singlet oxygen. | | Uses | An intermediate in the preparation of Piperidinyloxy free radical derivatives. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 37, p. 2050, 1972 DOI: 10.1021/jo00977a047 | | Purification Methods | The piperidine crystallises from water as a hydrate and crystallises from dry ether or *C6H6 as the anhydrous base. The hydrochloride has m 282-284o (from EtOH/H2O), and the formate has m 207o(dec, from EtOH/EtOAc). [Mailey & Day J Org Chem 22 1061 1957, Beilstein 21 I 195, 21 III/IV 146, 21/1 V 159.] |
| | 2,2,6,6-Tetramethyl-4-piperidinol Preparation Products And Raw materials |
| Raw materials | 4,4'-bis(2,2,6,6-tetramethylpiperidin-4-ol)-->1,2,2,6,6-Pentamethyl-4-piperidinol-->Triacetonamine-->2,2,6,6-Tetramethyl-4-piperidone hydrochloride-->N-BUTYL TRIACETONEDIAMINE-->DIPHENYLDIAZOMETHANE-->2,6-Dimethyl-2,5-heptadien-4-one-->Butylamine | | Preparation Products | LMI070-->4-Hydroxy-2,2,6,6-tetramethyl-piperidinooxy |
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