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(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol

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(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354
Email: support@targetmol.com
Products Intro: Product Name:Ophiocarpine；l-Ophiocarpine
CAS:478-13-7
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Basic information
Product Name:(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol
Synonyms:(13R)-5,8,13,13aα-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13-ol;(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol;9,10-Dimethoxy-2,3-(methylenedioxy)-13aα-berbin-13β-ol;Ophiocarpine;l-Ophiocarpine;6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13-ol, 5,8,13,13a-tetrahydro-9,10-dimethoxy-, (13R,13aR)-
CAS:478-13-7
MF:C20H21NO5
MW:355.38
EINECS:
Product Categories:
Mol File:478-13-7.mol
(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Structure
(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Chemical Properties
Melting point 188°C
Boiling point 517.6±50.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka13.38±0.20(Predicted)
Safety Information
MSDS Information
(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Usage And Synthesis
DescriptionThis protoberberine alkaloid is the major constituent of Corydalis ophiocarpa Hook. It has [α] 24 D - 284° (CHC13) and yields a sparingly soluble hydrochloride; a methiodide, m.p. 271°C (dec.) and the O-acetate, m.p. l41-3°C (165-7°C). It contains two methoxyl groups and one methylenedioxy group and when boiled with HCl furnishes a yellow base which, on oxidation with iodine and subsequent reduction, is converted into (±)-Canadine (q.v.). The alkaloid is therefore 13- hydroxycanadine, a structure confirmed by its oxidation to 6:7-methylenedioxy_x0002_l-keto-1: 2: 3 :4-tetrahydroisoquinoline (noroxyhydrastinine), m.p. 183°C, with KMn04' The optically inactive form crystallizes as colourless needles from MeOH-CHC13 , m.p. 252°C and also gives an O-acetate as needles from petroleum ether, m.p. 172-4°C.
ReferencesManske., Can. J. Res., 17B, 51 (1939)
Govindachari, Rajaduvai., J. Chern. Soc., 557 (1957)
Ohta, Toni, Morozumi., Tetrahedron Lett., 859 (1963)
(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol Preparation Products And Raw materials
Tag:(13R,13aR)-5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizin-13β-ol(478-13-7) Related Product Information