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| | (7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one Basic information |
| Product Name: | (7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one | | Synonyms: | Virgiline;(7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one;7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one, dodecahydro-9-hydroxy-, (7R,7aS,9S,14S,14aR)- | | CAS: | 2636-61-5 | | MF: | C15H24N2O2 | | MW: | 264.36 | | EINECS: | | | Product Categories: | | | Mol File: | 2636-61-5.mol | ![(7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one Structure](CAS/20180808/GIF/2636-61-5.gif) |
| | (7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one Chemical Properties |
| Melting point | 248 °C | | Boiling point | 467.7±45.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 14.80±0.20(Predicted) |
| | (7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one Usage And Synthesis |
| Description | A further alkaloid present in Virgilia capensis, this base has [α]D - 46° (EtOH).
One non-phenolic hydroxyl group is present and the alkaloid gives a hydrochloride,
m.p. 262°C; picrate, m.p. 188-9°C and the methiodide, m.p. 176°C.
The structure is that of 13-hydroxyaphylline and the pyrrole-2-carboxylic acid
ester is the alkaloid Oroboidine (q.v.). | | References | White., New Zealand J. Sci. Tech., 27B, 474 (1946)
Gerrans, Harley-Mason., Chem. & Ind., 1433 (1963)
Gerrans, Harley-Mason.,!. Chem. Soc., 2202 (1964) |
| | (7R,7aβ,9β,14aα)-Dodecahydro-9-hydroxy-7α,14α-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-6-one Preparation Products And Raw materials |
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