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| 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate Basic information |
Product Name: | 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate | Synonyms: | 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate;Silodosin Intermediate 1;2-[2-(2,2,2-trifluoroethoxy)phenoxy]-ethanol-1-Methanesulfonate;2-(2-TRIFLUOROETHOXYPHENOXY)ETHYLMETHANESULFONATE;Ethanol,2-[2-(2,2,2-trifluoroethoxy)phenoxy]-, 1-Methanesulfonate;2-(2-(2,2,2-Trifluoroethoxy);2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfote;2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate(for Silodoxin) | CAS: | 160969-03-9 | MF: | C11H13F3O5S | MW: | 314.28 | EINECS: | 801-482-2 | Product Categories: | | Mol File: | 160969-03-9.mol | |
| 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate Chemical Properties |
Melting point | 52.0 to 56.0 °C | Boiling point | 396.4±42.0 °C(Predicted) | density | 1.362 | storage temp. | 2-8°C | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Solid | color | White to Off-White |
| 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate Usage And Synthesis |
Uses | 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl Methanesulfonate is an intermediate of Silodosin (S465000) which is an α1a-adrenoceptor antagonist and used in the treatment of benign prostatic hypertophy. |
| 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethyl methanesulfonate Preparation Products And Raw materials |
Raw materials | 2-(2-HYDROXYETHOXY)PHENOL-->2-[2-(2,2,2-Trifluoroethoxy)phenoxy]ethanol-->1-Methoxy-2-(2,2,2-trifluoroethoxy)benzene-->2-(2-HYDROXYETHOXY)BENZALDEHYDE-->2-(2,2,2-Trifluoroethoxy)phenol-->Guaiacol-->Salicylaldehyde-->Catechol-->Methanesulfonyl chloride | Preparation Products | Acetic acid, 2-[2-(2,2,2-trifluoroethoxy)phenoxy]-, ethyl ester-->1-[3-(Benzoyloxy)propyl]-2,3-dihydro-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile |
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