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| | PIK-293 Basic information |
| Product Name: | PIK-293 | | Synonyms: | PIK-293;2-[(4-Amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;2-((4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one;PIK-293 USP/EP/BP;4(3H)-Quinazolinone, 2-[(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-;PIK-293;PIK293;PIK 293;2-[(4-aminopyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one;CS-539 | | CAS: | 900185-01-5 | | MF: | C22H19N7O | | MW: | 397.43 | | EINECS: | | | Product Categories: | Inhibitors;PI3K;mTOR;Akt | | Mol File: | 900185-01-5.mol |  |
| | PIK-293 Chemical Properties |
| density | 1.43 | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO > 10 mM | | form | Powder |
| | PIK-293 Usage And Synthesis |
| Description | PIK-293 is a cell-permeable, selective inhibitor of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110δ (IC50s = 100, 25, 10, and 0.24 μM for p110 subunit isoforms α, β, γ, and δ, respectively). | | Uses | PIK-293 is a phosphoinositide 3-kinase delta (PI3Kδ) inhibitor and the parent compound of PIK-294 (P437705). Inhibition of PI3K’s shows to be a promising approach for cancer therapy. |
| | PIK-293 Preparation Products And Raw materials |
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