- Ribose
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- $100.00 / 25kg
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2025-02-14
- CAS:24259-59-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 50000KG/month
- Ribose
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- $0.00 / 1KG
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2025-02-12
- CAS:24259-59-4
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 5000kg/month
- Ribose
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- $10.00 / 1KG
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2024-12-04
- CAS:24259-59-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5tons
Related articles - D-ribose and L-ribose
- Ribose (C5H10O5), with a molecular weight of 150.13 Dalton, is a pentose sugar comprising two enantiomers: L-ribose and D-ribo....
- Dec 17,2024
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| L-Ribose Basic information |
| L-Ribose Chemical Properties |
Melting point | 81-82 °C(lit.) | alpha | 20 º (c=2,water) | Boiling point | 191.65°C (rough estimate) | density | 1.1897 (rough estimate) | refractive index | 20 ° (C=1, H2O) | storage temp. | Inert atmosphere,Store in freezer, under -20°C | solubility | Methanol (Slightly), Water (Slightly) | form | Solid | pka | 12.22(at 25℃) | color | White to Off-White | Water Solubility | Soluble in water (100 mg/ml). | BRN | 1723084 | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. | CAS DataBase Reference | 24259-59-4(CAS DataBase Reference) |
| L-Ribose Usage And Synthesis |
Chemical Properties | white crystals or powder | Uses | It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. | Uses | L-[1-13C]ribose is a compound useful in organic synthesis. | Definition | ribose: A monosaccharide, C5H10O5, rarely occurring free in nature but important as a component of RNA (ribonucleic acid). Its derivative deoxyribose, C5H10O4, is equally important as a constituent of DNA (deoxyribonucleic acid), which carries the genetic code in chromosomes. | Definition | A monosaccharide; a component of RNA. | Biosynthesis | L-ribose is the enantiomer of D-ribose, which occurs naturally. It is a building block of many novel nucleotide analogue anti-viral drugs. Bio-production of L-ribose relies on a two-step reaction: (i) conversion of L-arabinose to L-ribulose by the catalytic action of L-arabinose isomerase (L-AI) and (ii) conversion of L-ribulose to L-ribose by the catalytic action of L-ribose isomerase (L-RI, EC 5.3.1.B3) or mannose-6-phosphate isomerase (MPI, EC 5.3.1.8, alternately named as phosphomannose isomerase). Among the two enzymes, L-RI is a rare enzyme discovered in 1996 by Professor Izumori's group, whereas MPI is an essential enzyme in metabolic pathways in humans and microorganisms[1].
| Synthesis |
A method for converting inexpensive, naturally occurring D-ribose into L-ribose is by interconverting the hydroxy group at Cl and the hydroxymethyl group at C5. L-Ribose is prepared from D-ribose by (a) forming a hydroxy-protected D-ribose, (b) reducing the hydroxy-protected D-ribose to a protected tetrol, (c) converting the tetrol to a tetraester, such as a tetraacetate; (d) hydrolyzing the protecting group to form a hydroxymethyl tetraester; (e) oxidizing the hydroxymethyl group to form a tetraester aldehyde; and (f) hydrolysing the ester groups to yield L-ribose.
| References | [1] M. Helanto. “Biotechnological production of l-ribose from l-arabinose.” Applied Microbiology and Biotechnology 83 1 (2009): 77–83.
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| L-Ribose Preparation Products And Raw materials |
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