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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride

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5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Suppliers list
Company Name: Zhuhai Hairuide Bioscience and Technology Co., Ltd
Tel: +8618928027945
Email: sales3@zhhairuide.com
Products Intro: Product Name:4,5,6,7-tetrahydro-5-methyl-Thiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
CAS:720720-96-7
Purity:99%+ Package:25KG;1KG;10KG Remarks:Hairuide manufacuturing, intermediates for Edoxaban +86 18928027945
Company Name: Anhui Ruihan Technology Co., Ltd
Tel: +8617756083858
Email: daisy@anhuiruihan.com
Products Intro: Product Name:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
CAS:720720-96-7
Purity:99% Package:1kg;30USD
Company Name: Capot Chemical Co.,Ltd.
Tel: 571-85586718 +8613336195806
Email: sales@capotchem.com
Products Intro: Product Name:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
CAS:720720-96-7
Purity:0.98 Package:100KG;10KG;5KG;1KG
Company Name: Beijing Cooperate Pharmaceutical Co.,Ltd
Tel: 010-60279497
Email: sales01@cooperate-pharm.com
Products Intro: Product Name:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
CAS:720720-96-7
Purity:98% Package:100G;1KG;50KG;100KG;1000KG
Company Name: Henan Tianfu Chemical Co.,Ltd.
Tel: +86-0371-55170693 +86-19937530512
Email: info@tianfuchem.com
Products Intro: Product Name:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
CAS:720720-96-7
Purity:99% Package:25KG;5KG;1KG

5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride manufacturers
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Basic information
Product Name:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
Synonyms:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride;EthanediaMide iMpurity B HCL;5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride;Thiazolo[5,4-c]pyridine-2-carboxylic acid, 4,5,6,7-tetrahydro-5-Methyl-, hydrochloride (1:1);5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride(for Edoxaban);4,5,6,7-tetrahydro-5-Methyl-Thiazolo[5,4-c]pyridin;4,5,6,7-tetrahydro-5-Methyl-Thiazolo[5,4-c]pyridine-2-carboxylic acid HCl;Edoxaban Impurity 18 Hydrochloride
CAS:720720-96-7
MF:C8H11ClN2O2S
MW:234.7
EINECS:858-363-3
Product Categories:
Mol File:720720-96-7.mol
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Structure
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Chemical Properties
Melting point 199.0 to 203.0 °C
Boiling point 175℃[at 101 325 Pa]
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Aqueous Acid (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly)
form Solid
color Pale Beige to Light Brown
Stability:Hygroscopic
Safety Information
HS Code 2934.10.2000
MSDS Information
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Usage And Synthesis
Uses5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is used as a reagent in the synthesis of N-(2-acylaminobenzyl or 2-acylaminoheterocyclylmethyl)thiophene-2-carboxamide derivatives as antithrombotics. It is also used as a reagent in the synthesis of diamide derivatives as FXa inhibitors. 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic Acid Hydrochloride is an intermediate for Edoxaban (E555520).
Preparation2-cyano-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride monohydrate (500.61 mg), ethanol (5 mL), and 4N aqueous lithium hydroxide (1.34 mL) were mixed at room temperature, and the resultant mixture was stirred at 50 °C for 7 hours. Until the reaction mixture was cooled with ice-water, 1N HCl in ethanol (7.5 mL) was added to the mixture. It was stirred for 1.5 hours. The precipitated crystals were collected by filtration, and were washed with ethanol (2 mL). The wet crystal was dried at room temperature under reduced pressure to obtain 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride.
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride
5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride Preparation Products And Raw materials
Raw materials4-Piperidinone, 3-broMo-1-Methyl-, hydrobroMide-->Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl--->2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-->Edoxaban Impurity 29-->1-Methyl-4-piperidone
Tag:5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride(720720-96-7) Related Product Information
EthanediaMide, N1-(5-chlo... Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate N-(5-Chloropyridin-2-yl)oxalaMic acid ethyl ester edoxaban Edoxaban Edoxaban Impurity 8 Oxalic acid 1-ethyl ester Edoxaban Impurity 29 INDEX NAME NOT YET ASSIGNED Edoxaban-d6 Edoxaban Impurity 16 (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester EthanediaMide iMpurity D EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid