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8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt

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8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:WAY 161503 hydrochloride
CAS:276695-22-8
Package:10 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:(Rac)-WAY-161503 (hydrochloride)
CAS:276695-22-8
Purity:NLT 98% Remarks:MC545959
Company Name: Nantong HI-FUTURE Biology Co., Ltd.
Tel: +undefined18051384581
Email: sales@chemhifuture.com
Products Intro: Product Name:WAY 161503 hydrochloride
CAS:276695-22-8
Purity:0.95 Package:5mg，10mg，100mg，500mg，1g，5g，10g，more
Company Name: Aladdin Scientific
Tel:
Email: tp@aladdinsci.com
Products Intro: Product Name:WAY 161503 hydrochloride
CAS:276695-22-8
Purity:98% Package:$151.9/10mg;$339.9/25mg;$625.9/50mg;Bulk package Remarks:98%
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:WAY 161503 hydrochloride
CAS:276695-22-8
Package:100mg;2500USD|50mg;1980USD|25mg;1520USD

8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt manufacturers
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Basic information
Product Name:8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt
Synonyms:8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt;8,9-Dichloro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one hydrochloride;(Rac)-WAY-161503 (hydrochloride)
CAS:276695-22-8
MF:C11H12Cl3N3O
MW:308.59148
EINECS:
Product Categories:
Mol File:276695-22-8.mol
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Structure
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Chemical Properties
storage temp. room temp
solubility DMSO: >10mg/mL
form powder
color white to off-white
Safety Information
WGK Germany nwg
MSDS Information
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Usage And Synthesis
UsesWAY 161503 Hydrochloride is a potent serotonin 5-HT2C receptor agonist with antiobesity effects. It is the salt analogue of WAY 161503 (D437235).
Biological ActivityThe 5-HT2C receptors have been implicated in conditions including obesity, anxiety, depression, OCD, schizophrenia, migraine, nociception and erectile dysfunction.
in vivo

(Rac)-WAY-161503 (3-30 mg/kg; i.p.; male C57BL/6J mice) hydrochloride dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082[1].

Animal Model:Male C57BL/6J mice with hallucinogen 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)[1]
Dosage:3 mg/kg, 10 mg/kg, 30 mg/kg
Administration:Intraperitoneal injection (i.p.)
Result:Antagonized the PGE2-mediated inhibition of LPS-induced TNF-α release from rat whole blood culture, in a dose-dependent way.
IC 505-HT2C Receptor: 4 nM (Ki); 5-HT2C Receptor: 12 nM (EC50)
storageDesiccate at RT
8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt Preparation Products And Raw materials
Tag:8,9-dichloro-2,3,4,4a-tetrahydro-1H-pyrazino[1,2-a]quinoxalin-5(6H)-one hydrochloride salt(276695-22-8) Related Product Information
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